Evidence map›Paper›PMID 36560821›Full record

ArticleViruses2022

Thromboembolic Events in Patients with Influenza: A Scoping Review.

Raffaella Rubino, Claudia Imburgia, Silvia Bonura, Marcello Trizzino, Chiara Iaria, Antonio Cascio

Open access · goldAbstract readScoping Review
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. COVID-19: a vascular nightmare unfolding.Frontiers in immunology · 2025
    Review
  13. Acute Aortic Thrombosis with Limb Ischemia in a Patient with Influenza A.European journal of case reports in internal medicine · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Thrombosis in Critically Ill Influenza Patients: Incidence and Risk Factors.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
  19. Serum Bilirubin Levels and Risk of Venous Thromboembolism among Influenza Patients: A Cohort Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Raffaella RubinoInfectious and Tropical Diseases Unit, AOU Policlinico "P-Giaccone", 90127 Palermo, Italy.
Claudia ImburgiaInfectious Diseases Unit, ARNAS Civico, 90127 Palermo, Italy.
Silvia BonuraInfectious and Tropical Diseases Unit, AOU Policlinico "P-Giaccone", 90127 Palermo, Italy.
Marcello TrizzinoInfectious and Tropical Diseases Unit, AOU Policlinico "P-Giaccone", 90127 Palermo, Italy.ORCID 0000-0002-8105-5139
Chiara IariaInfectious Diseases Unit, ARNAS Civico, 90127 Palermo, Italy.
Antonio CascioInfectious and Tropical Diseases Unit, AOU Policlinico "P-Giaccone", 90127 Palermo, Italy.ORCID 0000-0002-1992-1796
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionInfluenza is an acute respiratory infection that usually causes a short-term and self-limiting illness. However, in high-risk populations, this can lead to several complications, with an increase in mortality. Aside from the well-known extrapulmonary complications, several studies have investigated the relationship between influenza and acute cardio and cerebrovascular events. Reviews of the thromboembolic complications associated with influenza are lacking.

objectivesthe study aims to conduct a scoping review to analyze the epidemiological and clinical characteristics of patients suffering from influenza and thromboembolic complications. MATERIALS AND

methodsA computerized search of historical published cases using PubMed and the terms "influenza" or "flu" and "thrombosis", "embolism", "thromboembolism", "stroke", or "infarct" for the last twenty-five years was conducted. Only articles reporting detailed data on patients with thromboembolic complications of laboratory-confirmed influenza were considered eligible for inclusion in the scoping review.

resultsFifty-eight cases with laboratory documented influenza A or B and a related intravascular thrombosis were retrieved. Their characteristics were analyzed along with those of a patient who motivated our search. The localizations of thromboembolic events were pulmonary embolism 21/58 (36.2%), DVT 12/58 (20.6%), DVT and pulmonary embolism 3/58 (5.1%), acute ischemic stroke 11/58 (18.9%), arterial thrombosis 4/58 (6.8%), and acute myocardial infarction 5/58 (8.6%). DISCUSSION: Our findings are important in clarifying which thromboembolic complications are more frequent in adults and children with influenza. Symptoms of pulmonary embolism and influenza can be very similar, so a careful clinical evaluation is required for proper patient management, possible instrumental deepening, and appropriate pharmacological interventions, especially for patients with respiratory failure.

Indexed as

Ischemic StrokePulmonary EmbolismThromboembolismThrombosisVenous ThrombosisAdultChildHumansfluinfarctinfluenzastrokethromboembolismthrombosis

Identifiers

PMID36560821
PMCPMC9785394
OpenAlexW4312211084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.