Evidence map›Paper›PMID 36560792›Full record

ArticleViruses2022

Genomic Epidemiology of SARS-CoV-2 in Western Burkina Faso, West Africa.

Yacouba Sawadogo, Lokman Galal, Essia Belarbi, Arsène Zongo, Grit Schubert, Fabian Leendertz, Abdoulie Kanteh, Abdul Karim Sesay, Annette Erhart, Anne-Laure Bañuls and 4 more

Abstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yacouba SawadogoDepartement of Bacteriology and Virology, Souro Sanou University Hospital, Bobo Dioulasso 01 BP 676, Burkina Faso.ORCID 0000-0003-1813-5707
Lokman GalalLaboratoire de Bactériologie, Centre Hospitalier Universitaire de Montpellier, 34295 Montpellier, France.ORCID 0000-0002-2921-3849
Essia BelarbiRobert Koch Institute, 13353 Berlin, Germany.ORCID 0000-0002-9531-818X
Arsène ZongoMuraz Center, Bobo Dioulasso 01 BP 390, Burkina Faso.
Grit SchubertRobert Koch Institute, 13353 Berlin, Germany.
Fabian LeendertzHelmholtz Institut für One Health, 17489 Greifswald, Germany.
Abdoulie KantehGenomics Core Facility, Medical Research Council Unit the Gambia (MRCG), London School of Hygiene and Tropical Medicine, Fajara P.O. Box 273, The Gambia.ORCID 0000-0003-2050-5359
Abdul Karim SesayGenomics Core Facility, Medical Research Council Unit the Gambia (MRCG), London School of Hygiene and Tropical Medicine, Fajara P.O. Box 273, The Gambia.
Annette ErhartDisease Control and Elimination Theme, Medical Research Council Unit the Gambia (MRCG), London School of Hygiene and Tropical Medicine, Fajara P.O. Box 273, The Gambia.
Anne-Laure BañulsMaladies Infectieuses et Vecteurs: Ecologie, Génétique, Evolution et Contrôle (MIVEGEC), Université de Montpellier-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), 34394 Montpellier, France.ORCID 0000-0002-2106-8667
Zékiba TarnagdaLaboratoire National de Référence-Grippe (LNR-G), Institut de Recherche en Sciences de la Santé, Ouagadougou 03 BP 7192, Burkina Faso.ORCID 0000-0001-7320-3392
Sylvain GodreuilLaboratoire de Bactériologie, Centre Hospitalier Universitaire de Montpellier, 34295 Montpellier, France.ORCID 0000-0003-3436-0082
Halidou TintoCentre National de la Recherche Scientifique et Technologique/Institut de Recherche en Sciences de la Santé (CNRST/IRSS), Nanoro BP 18, Burkina Faso.
Abdoul-Salam OuedraogoDepartement of Bacteriology and Virology, Souro Sanou University Hospital, Bobo Dioulasso 01 BP 676, Burkina Faso.ORCID 0000-0002-8539-3768

Funding

Medical Research Council MC_PC_20045
6 · The paper itself

Abstract

backgroundAfter its initial detection in Wuhan, China, in December 2019, SARS-CoV-2 has spread rapidly, causing successive epidemic waves worldwide. This study aims to provide a genomic epidemiology of SARS-CoV-2 in Burkina Faso.

methodsThree hundred and seventy-seven SARS-CoV-2 genomes obtained from PCR-positive nasopharyngeal samples (PCR cycle threshold score < 35) collected between 5 May 2020, and 31 January 2022 were analyzed. Genomic sequences were assigned to phylogenetic clades using NextClade and to Pango lineages using pangolin. Phylogenetic and phylogeographic analyses were performed to determine the geographical sources and time of virus introduction in Burkina Faso.

resultsThe analyzed SARS-CoV-2 genomes can be assigned to 10 phylogenetic clades and 27 Pango lineages already described worldwide. Our analyses revealed the important role of cross-border human mobility in the successive SARS-CoV-2 introductions in Burkina Faso from neighboring countries.

conclusionsThis study provides additional insights into the genomic epidemiology of SARS-CoV-2 in West Africa. It highlights the importance of land travel in the spread of the virus and the need to rapidly implement preventive policies. Regional cross-border collaborations and the adherence of the general population to government policies are key to prevent new epidemic waves.

Indexed as

COVID-19SARS-CoV-2Burkina FasoGenomicsHumansPhylogenyPhylogeographyBurkina FasoCOVID-19genomic epidemiologySARS-CoV-2West Africawhole genome sequencing

Identifiers

PMID36560792
PMCPMC9782145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.