Evidence map›Paper›PMID 36560781›Full record

ArticleViruses2022

Oronasal or Intramuscular Immunization with a Thermo-Attenuated ASFV Strain Provides Full Clinical Protection against Georgia 2007/1 Challenge.

Olivier Bourry, Evelyne Hutet, Mireille Le Dimna, Pierrick Lucas, Yannick Blanchard, Amélie Chastagner, Frédéric Paboeuf, Marie-Frédérique Le Potier

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

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  12. Vaccines for African swine fever: an update.Frontiers in microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Olivier BourryAgence Nationale de Sécurité Sanitaire de l'Alimentation, de l'Environnement et du Travail (Anses), Laboratoire de Ploufragan-Plouzané-Niort, BP 53, 22440 Ploufragan, France.ORCID 0000-0003-0220-0922
Evelyne HutetAgence Nationale de Sécurité Sanitaire de l'Alimentation, de l'Environnement et du Travail (Anses), Laboratoire de Ploufragan-Plouzané-Niort, BP 53, 22440 Ploufragan, France.
Mireille Le DimnaAgence Nationale de Sécurité Sanitaire de l'Alimentation, de l'Environnement et du Travail (Anses), Laboratoire de Ploufragan-Plouzané-Niort, BP 53, 22440 Ploufragan, France.
Pierrick LucasAgence Nationale de Sécurité Sanitaire de l'Alimentation, de l'Environnement et du Travail (Anses), Laboratoire de Ploufragan-Plouzané-Niort, BP 53, 22440 Ploufragan, France.ORCID 0000-0002-2844-6157
Yannick BlanchardAgence Nationale de Sécurité Sanitaire de l'Alimentation, de l'Environnement et du Travail (Anses), Laboratoire de Ploufragan-Plouzané-Niort, BP 53, 22440 Ploufragan, France.
Amélie ChastagnerAgence Nationale de Sécurité Sanitaire de l'Alimentation, de l'Environnement et du Travail (Anses), Laboratoire de Ploufragan-Plouzané-Niort, BP 53, 22440 Ploufragan, France.
Frédéric PaboeufAgence Nationale de Sécurité Sanitaire de l'Alimentation, de l'Environnement et du Travail (Anses), Laboratoire de Ploufragan-Plouzané-Niort, BP 53, 22440 Ploufragan, France.
Marie-Frédérique Le PotierAgence Nationale de Sécurité Sanitaire de l'Alimentation, de l'Environnement et du Travail (Anses), Laboratoire de Ploufragan-Plouzané-Niort, BP 53, 22440 Ploufragan, France.ORCID 0000-0003-3929-9129
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

African swine fever (ASF) is a contagious viral disease of suids that induces high mortality in domestic pigs and wild boars. Given the current spread of ASF, the development of a vaccine is a priority. During an attempt to inactivate the Georgia 2007/1 strain via heat treatment, we fortuitously generated an attenuated strain called ASFV-989. Compared to Georgia, the ASFV-989 strain genome has a deletion of 7458 nucleotides located in the 5'-end encoding region of MGF 505/360, which allowed for developing a DIVA PCR system.

Indexed as

African Swine FeverAfrican Swine Fever VirusVaccinesViral VaccinesAnimalsImmunizationSus scrofaSwineVaccinesViral VaccinesASFintramuscularlive attenuated vaccineoronasal

Identifiers

PMID36560781
PMCPMC9784117
OpenAlexW4311480245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.