Evidence map›Paper›PMID 36560774›Full record

ArticleViruses2022

SARS-CoV-2 Omicron (B.1.1.529) Infection of Wild White-Tailed Deer in New York City.

Kurt J Vandegrift, Michele Yon, Meera Surendran Nair, Abhinay Gontu, Santhamani Ramasamy, Saranya Amirthalingam, Sabarinath Neerukonda, Ruth H Nissly, Shubhada K Chothe, Padmaja Jakka and 24 more

Abstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Evidence of SARS-CoV-2 Antibody in Mississippi White-Tailed Deer.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Association of vaccination, international travel, public health and social measures with lineage dynamics of SARS-CoV-2.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Kurt J VandegriftDepartment of Biology, The Pennsylvania State University, University Park, PA 16802, USA.
Michele YonAnimal Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Meera Surendran NairAnimal Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0003-4686-8414
Abhinay GontuAnimal Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0001-6260-7092
Santhamani RamasamyAnimal Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Saranya AmirthalingamAnimal Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Sabarinath NeerukondaUnited States Department of Health and Human Services, Silver Spring, MD 20993, USA.ORCID 0000-0002-1049-1929
Ruth H NisslyAnimal Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-3102-7447
Shubhada K ChotheAnimal Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-7109-7810
Padmaja JakkaAnimal Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Lindsey LaBellaAnimal Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Nicole LevineDepartment of Animal Science, The Pennsylvania State University, University Park, PA 16802, USA.
Sophie RodriguezDepartment of Animal Science, The Pennsylvania State University, University Park, PA 16802, USA.
Chen ChenDepartment of Chemical Engineering, The Pennsylvania State University, University Park, PA 16802, USA.
Veda Sheersh BoorlaDepartment of Chemical Engineering, The Pennsylvania State University, University Park, PA 16802, USA.
Tod StuberNational Veterinary Services Laboratories, Veterinary Services, U.S. Department of Agriculture, Ames, IA 50010, USA.
Jason R BoulangerWhite Buffalo, Inc., Chester, CT 06412, USA.ORCID 0000-0002-7602-3124
Nathan KotschwarWhite Buffalo, Inc., Chester, CT 06412, USA.
Sarah Grimké AucoinCity of New York Parks & Recreation, New York, NY 10029, USA.
Richard SimonCity of New York Parks & Recreation, New York, NY 10029, USA.
Katrina L ToalCity of New York Parks & Recreation, New York, NY 10029, USA.
Randall J OlsenLaboratory of Molecular and Translational Human Infectious Disease Research, Center for Infectious Diseases, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX 77030, USA.
James J DavisConsortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA.
Dashzeveg BoldDepartment of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0001-9113-7296
Natasha N GaudreaultDepartment of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0002-7195-785X
Krishani Dinali PereraDepartment of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS 66506, USA.
Yunjeong KimDepartment of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0002-2977-4400
Kyeong-Ok ChangDepartment of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS 66506, USA.
Costas D MaranasDepartment of Chemical Engineering, The Pennsylvania State University, University Park, PA 16802, USA.
Juergen A RichtDepartment of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0001-7308-5672
James M MusserLaboratory of Molecular and Translational Human Infectious Disease Research, Center for Infectious Diseases, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX 77030, USA.
Peter J HudsonDepartment of Biology, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0003-0468-3403
Vivek KapurThe Center for Infectious Disease Dynamics, Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Suresh V KuchipudiThe Center for Infectious Disease Dynamics, Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-8640-254X

Funding

BIOINFORMATICS RESOURCE CENTERS FOR INFECTIOUS DISEASES: SARS-CoV-2 ACTIVITIES75N93019C00076 · NIAID · UNIVERSITY OF CHICAGO · PI STEVENS, RICK · 2019 to 2023
$32.6M
Sex-specific effects of obestity on Influenza A virus infection and immunityP20GM130448 · NIGMS · KANSAS STATE UNIVERSITY · PI REVATHI GOVIND · 2020 to 2026
$15.8M
Carbon nanotube integrated microdevice for next generation sequencing based virus discoveryR01AI134911 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI ZHENG, SIYANG · 2018 to 2022
$2.0M
Infection and prevalence of a new segmented flavivirus in the United StatesR21AI156406 · NIAID · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI KAPOOR, AMIT · 2021 to 2022
$440k
NIAID NIH HHS 75N93019C00076NIAID NIH HHS HHSN272201400006CNIAID NIH HHS R01 AI134911NIAID NIH HHS R21 AI156406NIGMS NIH HHS P20 GM130448NIGMS NIH HHS P20GM130448NIH HHS 7R01AI134911
6 · The paper itself

Abstract

There is mounting evidence of SARS-CoV-2 spillover from humans into many domestic, companion, and wild animal species. Research indicates that humans have infected white-tailed deer, and that deer-to-deer transmission has occurred, indicating that deer could be a wildlife reservoir and a source of novel SARS-CoV-2 variants. We examined the hypothesis that the Omicron variant is actively and asymptomatically infecting the free-ranging deer of New York City. Between December 2021 and February 2022, 155 deer on Staten Island, New York, were anesthetized and examined for gross abnormalities and illnesses. Paired nasopharyngeal swabs and blood samples were collected and analyzed for the presence of SARS-CoV-2 RNA and antibodies. Of 135 serum samples, 19 (14.1%) indicated SARS-CoV-2 exposure, and 11 reacted most strongly to the wild-type B.1 lineage. Of the 71 swabs, 8 were positive for SARS-CoV-2 RNA (4 Omicron and 4 Delta). Two of the animals had active infections and robust neutralizing antibodies, revealing evidence of reinfection or early seroconversion in deer. Variants of concern continue to circulate among and may reinfect US deer populations, and establish enzootic transmission cycles in the wild: this warrants a coordinated One Health response, to proactively surveil, identify, and curtail variants of concern before they can spill back into humans.

Indexed as

COVID-19DeerAnimalsAnimals, WildHumansNew York CityRNA, ViralSARS-CoV-2RNA, Viraldisease ecologyenzootic transmissionOdocoileus virginianusomicronreinfectionreservoir competenceSARS-CoV-2spillovervariant of concernwhite-tailed deerzoonotic

Identifiers

PMID36560774
PMCPMC9785669

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.