Evidence map›Paper›PMID 36560693›Full record

ArticleViruses2022

What's Next for Flu? Out-of-Season Circulation of Influenza Viruses in Southern Italy, August 2022.

Daniela Loconsole, Francesca Centrone, Valerio Aprile, Anna Sallustio, Daniele Casulli, Marisa Accogli, Davide Sacco, Riccardo Zagaria, Maria Chironna

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Daniela LoconsoleDepartment of Interdisciplinary Medicine, Hygiene Section, University of Bari, 70124 Bari, Italy.ORCID 0000-0003-2057-9745
Francesca CentroneDepartment of Interdisciplinary Medicine, Hygiene Section, University of Bari, 70124 Bari, Italy.ORCID 0000-0003-3018-5408
Valerio AprileDepartment of Prevention, Local Health Unit of Lecce, 73100 Lecce, Italy.
Anna SallustioHygiene Unit, Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, 70124 Bari, Italy.
Daniele CasulliHygiene Unit, Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, 70124 Bari, Italy.
Marisa AccogliDepartment of Interdisciplinary Medicine, Hygiene Section, University of Bari, 70124 Bari, Italy.
Davide SaccoDepartment of Interdisciplinary Medicine, Hygiene Section, University of Bari, 70124 Bari, Italy.
Riccardo ZagariaDepartment of Interdisciplinary Medicine, Hygiene Section, University of Bari, 70124 Bari, Italy.
Maria ChironnaDepartment of Interdisciplinary Medicine, Hygiene Section, University of Bari, 70124 Bari, Italy.ORCID 0000-0002-1043-1256
University of Bari Aldo Moro · ITAzienda Universitaria Ospedaliera Consorziale - Policlinico Bari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has modified the seasonal pattern of respiratory infections. The objective of the present study is to characterize the out-of-season circulation of influenza viruses and an influenza outbreak that occurred in southern Italy in August 2022. Nasopharyngeal swabs collected from patients with influenza-like illnesses (ILI) were tested for the presence of influenza and other respiratory viruses. Epidemiological investigations on 85 patients involved in an influenza outbreak were performed. Sequencing and phylogenetic analysis of hemagglutinin genes was undertaken on samples positive for influenza A. In August 2022, in the Apulia region (Italy), influenza A infection was diagnosed in 19 patients, 18 infected with A/H3N2 and one with A/H1N1pdm09 virus. Seven influenza-positive patients were hospitalized with ILI. A further 17 symptomatic subjects, associated with an influenza outbreak, were also tested; 11 were positive for influenza A/H3N2 virus. Phylogenetic analysis of 12 of the A/H3N2 sequences showed that they all belonged to subclade 3C.2a1b.2a.2. The A/H1N1pdm09 strain belonged to subclade 6B.1A.5a.2. The out-of-season circulation of the influenza virus during the summer months could be linked to changing dynamics in the post-COVID-19 era, as well as to the impact of climate change. Year-round surveillance of respiratory viruses is needed to monitor this phenomenon and to provide effective prevention strategies.

Indexed as

COVID-19Influenza A virusInfluenza, HumanHumansInfluenza A Virus, H3N2 SubtypeItalyPandemicsPhylogenySeasonsepidemiologyinfluenza A virusoutbreakout-of-season circulationphylogenetic analysisrespiratory virusesSARS-CoV-2

Identifiers

PMID36560693
PMCPMC9783519
OpenAlexW4311014317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.