Evidence map›Paper›PMID 36560641›Full record

ReviewViruses2022

Reaching the Final Endgame for Constant Waves of COVID-19.

Norman Arthur Ratcliffe, Helena Carla Castro, Marcelo Salabert Gonzalez, Cicero Brasileiro Mello, Paul Dyson

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Norman Arthur RatcliffeBiology Institute, Universidade Federal Fluminense, Niterói 24210-130, RJ, Brazil.
Helena Carla CastroBiology Institute, Universidade Federal Fluminense, Niterói 24210-130, RJ, Brazil.
Marcelo Salabert GonzalezBiology Institute, Universidade Federal Fluminense, Niterói 24210-130, RJ, Brazil.
Cicero Brasileiro MelloBiology Institute, Universidade Federal Fluminense, Niterói 24210-130, RJ, Brazil.
Paul DysonInstitute of Life Science, Medical School, Swansea University, Singleton Park, Swansea SA2 8PP, UK.ORCID 0000-0002-0558-2666
Universidade Federal Fluminense · BRSwansea University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite intramuscular vaccines saving millions of lives, constant devastating waves of SARS-CoV-2 infections continue. The elimination of COVID-19 is challenging, but necessary in order to avoid millions more people who would suffer from long COVID if we fail. Our paper describes rapidly advancing and innovative therapeutic strategies for the early stage of infection with COVID-19 so that tolerating continuing cycles of infection should be unnecessary in the future. These therapies include new vaccines with broader specificities, nasal therapies and antiviral drugs some targeting COVID-19 at the first stage of infection and preventing the virus entering the body in the first place. Our article describes the advantages and disadvantages of each of these therapeutic options which in various combinations could eventually prevent renewed waves of infection. Finally, important consideration is given to political, social and economic barriers that since 2020 hindered vaccine application and are likely to interfere again with any COVID-19 endgame.

Indexed as

COVID-19Antiviral AgentsHumansPost-Acute COVID-19 SyndromeSARS-CoV-2Antiviral Agentsantiviral drugsCOVID-19 eliminationnasal therapiesnew therapeutic optionsOmicronpolitical and social hindrancesSARS-CoV-2vaccines

Identifiers

PMID36560641
PMCPMC9783511
OpenAlexW4310215419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.