Evidence map›Paper›PMID 36560537›Full record

ReviewVaccines2022

Therapeutic Potentials of Immunometabolomic Modulations Induced by Tuberculosis Vaccination.

Bhupendra Singh Rawat, Deepak Kumar, Vijay Soni, Eric H Rosenn

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Bhupendra Singh RawatCenter for Immunity and Inflammation, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.
Deepak KumarDepartment of Zoology, University of Rajasthan, Jaipur 302004, Rajasthan, India.ORCID 0000-0001-5868-2057
Vijay SoniDivision of Infectious Diseases, Weill Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Eric H RosennSchool of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
Cornell University · USRutgers, The State University of New Jersey · USTel Aviv University · ILUniversity of Rajasthan · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolomics is emerging as a promising tool to understand the effect of immunometabolism for the development of novel host-directed alternative therapies. Immunometabolism can modulate both innate and adaptive immunity in response to pathogens and vaccinations. For instance, infections can affect lipid and amino acid metabolism while vaccines can trigger bile acid and carbohydrate pathways. Metabolomics as a vaccinomics tool, can provide a broader picture of vaccine-induced biochemical changes and pave a path to potentiate the vaccine efficacy. Its integration with other systems biology tools or treatment modes can enhance the cure, response rate, and control over the emergence of drug-resistant strains.

Indexed as

Bacillus Calmette-Guerinepigenetics and immunityimmunometabolismmetabolomicsMycobacterium tuberculosistrained immunitytuberculosisvaccine metabolismvaccinomics

Identifiers

PMID36560537
PMCPMC9781011
OpenAlexW4311397561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.