Evidence map›Paper›PMID 36560516›Full record

ArticleVaccines2022

Bioinformatics Designing and Molecular Modelling of a Universal mRNA Vaccine for SARS-CoV-2 Infection.

Elijah Kolawole Oladipo, Micheal Oluwafemi Adeniyi, Mercy Temiloluwa Ogunlowo, Boluwatife Ayobami Irewolede, Victoria Oluwapelumi Adekanola, Glory Samuel Oluseyi, Janet Abisola Omilola, Anietie Femi Udoh, Seun Elijah Olufemi, Daniel Adewole Adediran and 5 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

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  10. Cancer/Testis Antigens as Targets for RNA-Based Anticancer Therapy.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Elijah Kolawole OladipoGenomics Unit, Helix Biogen Institute, Ogbomoso 210214, Nigeria.
Micheal Oluwafemi AdeniyiGenomics Unit, Helix Biogen Institute, Ogbomoso 210214, Nigeria.
Mercy Temiloluwa OgunlowoGenomics Unit, Helix Biogen Institute, Ogbomoso 210214, Nigeria.
Boluwatife Ayobami IrewoledeGenomics Unit, Helix Biogen Institute, Ogbomoso 210214, Nigeria.ORCID 0000-0003-0729-5748
Victoria Oluwapelumi AdekanolaGenomics Unit, Helix Biogen Institute, Ogbomoso 210214, Nigeria.
Glory Samuel OluseyiGenomics Unit, Helix Biogen Institute, Ogbomoso 210214, Nigeria.
Janet Abisola OmilolaGenomics Unit, Helix Biogen Institute, Ogbomoso 210214, Nigeria.
Anietie Femi UdohDepartment of Biochemistry, Obafemi Awolowo University, Ile-Ife 220005, Nigeria.
Seun Elijah OlufemiGenomics Unit, Helix Biogen Institute, Ogbomoso 210214, Nigeria.ORCID 0000-0002-8292-2345
Daniel Adewole AdediranGenomics Unit, Helix Biogen Institute, Ogbomoso 210214, Nigeria.ORCID 0000-0003-2907-3783
Aanuoluwapo OlonadeDepartment of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso 210214, Nigeria.
Usman Abiodun IdowuGenomics Unit, Helix Biogen Institute, Ogbomoso 210214, Nigeria.
Olatunji M KolawoleDepartment of Microbiology, University of Ilorin, Ilorin 234031, Nigeria.ORCID 0000-0003-1914-6766
Julius Kola OlokeDepartment of Natural Science, Precious Cornerstone, Ibadan 200132, Nigeria.
Helen OnyeakaSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.ORCID 0000-0003-3846-847X
Ladoke Akintola University of Technology · NGAdeleke University · NGObafemi Awolowo University · NGUniversity of Birmingham · GBUniversity of Ilorin · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At this present stage of COVID-19 re-emergence, designing an effective candidate vaccine for different variants of SARS-CoV-2 is a study worthy of consideration. This research used bioinformatics tools to design an mRNA vaccine that captures all the circulating variants and lineages of the virus in its construct. Sequences of these viruses were retrieved across the six continents and analyzed using different tools to screen for the preferable CD8

Indexed as

bioinformaticslineagesmRNA vaccineSARS-CoV-2variants

Identifiers

PMID36560516
PMCPMC9785986
OpenAlexW4311962076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.