Evidence map›Paper›PMID 36560451›Full record

ArticleVaccines2022

Immediate Adverse Events Following COVID-19 Vaccination in Australian Pharmacies: A Retrospective Review.

Alexander T Gallo, Lisa Scanlon, Jade Clifford, Lawson Patten-Williams, Lachlan Tweedie, Dani Li, Sandra M Salter

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alexander T GalloDiscipline of Pharmacy, School of Allied Health, University of Western Australia, Crawley 6009, Australia.ORCID 0000-0001-8647-4968
Lisa ScanlonMedAdvisor International, Camberwell 3124, Australia.
Jade CliffordDiscipline of Pharmacy, School of Allied Health, University of Western Australia, Crawley 6009, Australia.
Lawson Patten-WilliamsDiscipline of Pharmacy, School of Allied Health, University of Western Australia, Crawley 6009, Australia.
Lachlan TweedieDiscipline of Pharmacy, School of Allied Health, University of Western Australia, Crawley 6009, Australia.
Dani LiMedAdvisor International, Camberwell 3124, Australia.
Sandra M SalterDiscipline of Pharmacy, School of Allied Health, University of Western Australia, Crawley 6009, Australia.ORCID 0000-0002-5840-6797
The University of Western Australia · AU

Funding

Government of Western Australia FHRIFGCOVID19
6 · The paper itself

Abstract

backgroundFour COVID-19 vaccines are approved for use in Australia: Pfizer-BioNTech BNT162b2 (Comirnaty), AstraZeneca ChAdOx1 (Vaxzevria), Moderna mRNA-1273 (Spikevax), and Novavax NVX-CoV2373 (Nuvaxovid). We sought to examine the type and management of immediate adverse events following immunisation (I-AEFI) after COVID-19 vaccination.

methodsRetrospective review of I-AEFI recorded between July 2021 and June 2022 in 314 community pharmacies in Australia.

resultsI-AEFI were recorded in 0.05% (n = 526/977,559) of all COVID-19 vaccinations (highest: AstraZeneca (n = 173/161,857; 0.11%); lowest: Pfizer (n = 50/258,606; 0.02%)). The most common reactions were: (1) syncope, after the first dose of AstraZeneca (n = 105/67,907; 0.15%), Moderna (n = 156/108,339; 0.14%), and Pfizer (n = 22/16,287; 0.14%); and (2) Nausea/vomiting after the first dose of Pfizer (n = 9/16,287; 0.06%), Moderna (n = 55/108,339; 0.05%), and AstraZeneca (n = 31/67,907; 0.05%) vaccines. A total of 23 anaphylactic reactions were recorded (n = 23/977,559; 0.002%), and 59 additional I-AEFI were identified using MedDRA

conclusionThe most commonly recorded I-AEFI was syncope after COVID-19 vaccination in pharmacy; I-AEFI are similar to those previously reported. Pharmacists identified and managed serious and non-serious I-AEFI appropriately and comprehensively.

Indexed as

adverse event following immunizationanaphylactic reactionanaphylaxisconvulsionCOVID-19pharmacistpharmacyseizuresyncopevaccination

Identifiers

PMID36560451
PMCPMC9787804
OpenAlexW4311005646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.