Evidence map›Paper›PMID 36560420›Full record

ReviewVaccines2022

Recent Advances in Cancer Vaccines: Challenges, Achievements, and Futuristic Prospects.

Madhu Gupta, Abhishek Wahi, Priyanka Sharma, Riya Nagpal, Neha Raina, Monika Kaurav, Jaydeep Bhattacharya, Sonia M Rodrigues Oliveira, Karma G Dolma, Alok K Paul and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 5 countries.

Madhu GuptaDepartment of Pharmaceutics, School of Pharmaceutical Sciences, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India.ORCID 0000-0002-8503-0609
Abhishek WahiDepartment of Pharmaceutics, School of Pharmaceutical Sciences, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India.ORCID 0000-0002-8144-8135
Priyanka SharmaDepartment of Pharmaceutics, School of Pharmaceutical Sciences, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India.
Riya NagpalDepartment of Pharmaceutics, School of Pharmaceutical Sciences, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India.ORCID 0000-0001-6585-5438
Neha RainaDepartment of Pharmaceutics, School of Pharmaceutical Sciences, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India.
Monika KauravDepartment of Pharmaceutics, KIET Group of Institutions Delhi-NCR, Meerut Road (NH-58), Ghaziabad 201206, India.ORCID 0000-0002-3277-6896
Jaydeep BhattacharyaSchool of Biotechnology, Jawaharlal Nehru University, New Delhi 110067, India.
Sonia M Rodrigues OliveiraCICECO-Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-0707-5203
Karma G DolmaDepartment of Microbiology, Sikkim Manipal Institute of Medical Sciences, Sikkim Manipal University, Gangtok 737102, India.ORCID 0000-0001-7007-0774
Alok K PaulSchool of Pharmacy and Pharmacology, University of Tasmania, Hobart, TAS 7001, Australia.ORCID 0000-0002-6090-2407
Maria de Lourdes PereiraCICECO-Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0001-6703-7869
Polrat WilairatanaDepartment of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.ORCID 0000-0002-2730-7788
Mohammed RahmatullahDepartment of Biotechnology & Genetic Engineering, University of Development Alternative, Lalmatia, Dhaka 1207, Bangladesh.ORCID 0000-0002-0216-7977
Veeranoot NissapatornSchool of Allied Health Sciences and World Union for Herbal Drug Discovery (WUHeDD), Walailak University, Nakhon Si Thammarat 80160, Thailand.
Delhi Pharmaceutical Science and Research University · INHunter Medical Research Institute · AUInstitute of Medical Sciences · INJawaharlal Nehru University · INMahidol University · THUniversity of Aveiro · PTUniversity of Development Alternative · BDUniversity of Tasmania · AUWalailak University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a chronic disease, and it can be lethal due to limited therapeutic options. The conventional treatment options for cancer have numerous challenges, such as a low blood circulation time as well as poor solubility of anticancer drugs. Therapeutic cancer vaccines emerged to try to improve anticancer drugs' efficiency and to deliver them to the target site. Cancer vaccines are considered a viable therapeutic technique for most solid tumors. Vaccines boost antitumor immunity by delivering tumor antigens, nucleic acids, entire cells, and peptides. Cancer vaccines are designed to induce long-term antitumor memory, causing tumor regression, eradicate minimal residual illness, and prevent non-specific or unpleasant effects. These vaccines can assist in the elimination of cancer cells from various organs or organ systems in the body, with minimal risk of tumor recurrence or metastasis. Vaccines and antigens for anticancer therapy are discussed in this review, including current vaccine adjuvants and mechanisms of action for various types of vaccines, such as DNA- or mRNA-based cancer vaccines. Potential applications of these vaccines focusing on their clinical use for better therapeutic efficacy are also discussed along with the latest research available in this field.

Indexed as

antigencancerimmunotherapynucleic acidpeptidesvaccine

Identifiers

PMID36560420
PMCPMC9788126
OpenAlexW4310211652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.