Evidence map›Paper›PMID 36559667›Full record

ArticlePlants (Basel, Switzerland)2022

Comparative Transcriptome and Co-Expression Network Analyses Reveal the Molecular Mechanism of Calcium-Deficiency-Triggered Tipburn in Chinese Cabbage (

Shu Zhang, Hanzhong Gao, Lixia Wang, Yihui Zhang, Dandan Zhou, Ali Anwar, Jingjuan Li, Fengde Wang, Cheng Li, Ye Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. BrCNGC12 and BrCNGC16 mediate CaPlant biotechnology journal · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Shu ZhangInstitute of Vegetables, Shandong Key Laboratory of Greenhouse Vegetable Biology, Shandong Branch of National Vegetable Improvement Center, Huanghuai Region Vegetable Scientific Station of Ministry of Agriculture (Shandong), Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Hanzhong GaoColumbian College of Arts & Sciences, Phillips Hall, The George Washington University, 801 22nd St. NW., Washington, DC 20052, USA.
Lixia WangInstitute of Vegetables, Shandong Key Laboratory of Greenhouse Vegetable Biology, Shandong Branch of National Vegetable Improvement Center, Huanghuai Region Vegetable Scientific Station of Ministry of Agriculture (Shandong), Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Yihui ZhangInstitute of Vegetables, Shandong Key Laboratory of Greenhouse Vegetable Biology, Shandong Branch of National Vegetable Improvement Center, Huanghuai Region Vegetable Scientific Station of Ministry of Agriculture (Shandong), Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Dandan ZhouCollege of Life Sciences, Shandong Normal University, Jinan 250061, China.
Ali AnwarInstitute of Vegetables, Shandong Key Laboratory of Greenhouse Vegetable Biology, Shandong Branch of National Vegetable Improvement Center, Huanghuai Region Vegetable Scientific Station of Ministry of Agriculture (Shandong), Shandong Academy of Agricultural Sciences, Jinan 250100, China.ORCID 0000-0002-8630-2338
Jingjuan LiInstitute of Vegetables, Shandong Key Laboratory of Greenhouse Vegetable Biology, Shandong Branch of National Vegetable Improvement Center, Huanghuai Region Vegetable Scientific Station of Ministry of Agriculture (Shandong), Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Fengde WangInstitute of Vegetables, Shandong Key Laboratory of Greenhouse Vegetable Biology, Shandong Branch of National Vegetable Improvement Center, Huanghuai Region Vegetable Scientific Station of Ministry of Agriculture (Shandong), Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Cheng LiInstitute of Vegetables, Shandong Key Laboratory of Greenhouse Vegetable Biology, Shandong Branch of National Vegetable Improvement Center, Huanghuai Region Vegetable Scientific Station of Ministry of Agriculture (Shandong), Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Ye ZhangCollege of Life Science, Huangshan University, Huangshan 245061, China.
Jianwei GaoInstitute of Vegetables, Shandong Key Laboratory of Greenhouse Vegetable Biology, Shandong Branch of National Vegetable Improvement Center, Huanghuai Region Vegetable Scientific Station of Ministry of Agriculture (Shandong), Shandong Academy of Agricultural Sciences, Jinan 250100, China.ORCID 0000-0001-7766-0742
Shandong Academy of Agricultural Sciences · CNShandong Normal University · CNGeorge Washington University · USHuangshan University · CN

Funding

Agricultural Science and Technology Innovation Project of SAAS CXGC2021B17Agricultural Science and Technology Innovation Project of SAAS CXGC2022E08Agricultural Science and Techonology Innovation Project of SAAS CXGC2021A10China Agriculture Research System CARS-23-G14Key R & D Program of Shandong Province, China 2019GHZ014Modern Agricultural Industrial Technology System Funding of Shandong Province, China SDAIT-02-022-04Natural Science Research Project of Huangshan University 2019xkjq011Natural Science Research Project of Huangshan University, China 2019xkjq011Natural Science Research Project of Shandong Province ZR2020QC145Prospect of Shandong Seed Project, China 2019LZGC0060101Taishan Scholars Program of Shandong Province, China tsqn201909167The Open Fund of State Key Laboratory of Tea Plant Biology and Utilization SKLTOF20190128
6 · The paper itself

Abstract

Chinese cabbage tipburn is characterized by the formation of necrotic lesions on the margin of leaves, including on the insides of the leafy head. This physiological disorder is associated with a localized calcium deficiency during leaf development. However, little information is available regarding the molecular mechanisms governing Ca-deficiency-triggered tipburn. This study comprehensively analysed the transcriptomic comparison between control and calcium treatments (CK and 0 mM Ca) in Chinese cabbage to determine its molecular mechanism in tipburn. Our analysis identified that the most enriched gene ontology (GO) categories are photosynthesis, thylakoid and cofactor binding. Moreover, the KEGG pathway was most enriched in photosynthesis, carbon metabolism and carbon fixation. We also analyzed the co-expression network by functional categories and identified ten critical hub differentially expressed genes (DEGs) in each gene regulatory network (GRN). These DEGs might involve abiotic stresses, developmental processes, cell wall metabolism, calcium distribution, transcription factors, plant hormone biosynthesis and signal transduction pathways. Under calcium deficiency, CNX1, calmodulin-binding proteins and CMLs family proteins were downregulated compared to CK. In addition, plant hormones such as GA, JA, BR, Auxin and ABA biosynthesis pathways genes were downregulated under calcium treatment. Likewise,

Indexed as

calcium deficiencyChinese cabbageco-expression analysisRNA-seqtipburn

Identifiers

PMID36559667
PMCPMC9785529
OpenAlexW4312211691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.