Evidence map›Paper›PMID 36559309›Full record

ArticlePharmaceutics2022

Thymoquinone: Hydroxypropyl-β-cyclodextrin Loaded Bacterial Cellulose for the Management of Wounds.

Sam Swingler, Abhishek Gupta, Hazel Gibson, Marek Kowalczuk, Grazyna Adamus, Wayne Heaselgrave, Iza Radecka

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Analysis of Pharmacological Properties ofLife (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Sam SwinglerDepartment of Biology, Chemistry and Forensic Science, School of Sciences, Faculty of Science and Engineering, University of Wolverhampton, Wolverhampton WV1 1LY, UK.ORCID 0000-0002-2447-2278
Abhishek GuptaSchool of Allied Health and Midwifery, Faculty of Education, Health and Wellbeing, University of Wolverhampton, Walsall WS1 3BD, UK.ORCID 0000-0001-7901-1818
Hazel GibsonDepartment of Biology, Chemistry and Forensic Science, School of Sciences, Faculty of Science and Engineering, University of Wolverhampton, Wolverhampton WV1 1LY, UK.ORCID 0000-0002-4710-5868
Marek KowalczukCentre of Polymer and Carbon Materials, Polish Academy of Sciences, M. Curie-Sklodowskiej 34, 41-819 Zabrze, Poland.ORCID 0000-0002-2877-7466
Grazyna AdamusCentre of Polymer and Carbon Materials, Polish Academy of Sciences, M. Curie-Sklodowskiej 34, 41-819 Zabrze, Poland.ORCID 0000-0001-5439-7400
Wayne HeaselgraveDepartment of Biomedical Science, University of Wolverhampton, Wolverhampton WV1 1LY, UK.ORCID 0000-0003-0025-1769
Iza RadeckaDepartment of Biology, Chemistry and Forensic Science, School of Sciences, Faculty of Science and Engineering, University of Wolverhampton, Wolverhampton WV1 1LY, UK.ORCID 0000-0003-3257-8803
University of Wolverhampton · GBCentre of Polymer and Carbon Materials · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The need for more advantageous and pharmaceutically active wound dressings is a pressing matter in the area of wound management. In this study, we explore the possibility of incorporating thymoquinone within bacterial cellulose, utilising cyclodextrins as a novel method of solubilising hydrophobic compounds. The thymoquinone was not soluble in water, so was incorporated within hydroxypropyl-β-cyclodextrin before use. Thymoquinone: hydroxypropyl-β-cyclodextrin inclusion complex produced was found to be soluble in water up to 7% (

Indexed as

anti-fungalbacterial cellulosebiomaterialsbiopolymercontrolled drug releaseexperimental dermatologywound dressing

Identifiers

PMID36559309
PMCPMC9781873
OpenAlexW4311616642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.