Evidence map›Paper›PMID 36559294›Full record

ArticlePharmaceutics2022

Dinuclear Iron Complexes of Iminopyridine-Based Ligands as Selective Cytotoxins for Tumor Cells and Inhibitors of Cancer Cell Migration.

Jessica Castro, Marlon Bravo, Meritxell Albertí, Anaís Marsal, María José Alonso-De Gennaro, Oriol Martínez-Ferraté, Carmen Claver, Piet W N M van Leeuwen, Isabel Romero, Antoni Benito and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jessica CastroLaboratori d'Enginyeria de Proteïnes, Departament de Biologia, Facultat de Ciències, Universitat de Girona, Campus de Montilivi, C/Maria Aurèlia Capmany, 40, 17003 Girona, Spain.ORCID 0000-0003-4766-2311
Marlon BravoLaboratori d'Enginyeria de Proteïnes, Departament de Biologia, Facultat de Ciències, Universitat de Girona, Campus de Montilivi, C/Maria Aurèlia Capmany, 40, 17003 Girona, Spain.ORCID 0000-0002-0065-9812
Meritxell AlbertíLaboratori d'Enginyeria de Proteïnes, Departament de Biologia, Facultat de Ciències, Universitat de Girona, Campus de Montilivi, C/Maria Aurèlia Capmany, 40, 17003 Girona, Spain.ORCID 0000-0003-4639-815X
Anaís MarsalLaboratori d'Enginyeria de Proteïnes, Departament de Biologia, Facultat de Ciències, Universitat de Girona, Campus de Montilivi, C/Maria Aurèlia Capmany, 40, 17003 Girona, Spain.
María José Alonso-De GennaroLaboratori d'Enginyeria de Proteïnes, Departament de Biologia, Facultat de Ciències, Universitat de Girona, Campus de Montilivi, C/Maria Aurèlia Capmany, 40, 17003 Girona, Spain.
Oriol Martínez-FerratéDepartament de Quimica Física e Inorgànica, Universitat Rovira i Virgili, Campus Sescelades, 43007 Tarragona, Spain.
Carmen ClaverDepartament de Quimica Física e Inorgànica, Universitat Rovira i Virgili, Campus Sescelades, 43007 Tarragona, Spain.
Piet W N M van LeeuwenInstitut Català d'Investigació Química (ICIQ), Avinguda dels Països Catalans, 16, 43007 Tarragona, Spain.ORCID 0000-0002-2165-7090
Isabel RomeroDepartament de Química and Serveis Tècnics de Recerca, Universitat de Girona, Campus de Montilivi, C/Maria Aurèlia Capmany, 69, 17003 Girona, Spain.ORCID 0000-0003-4805-8394
Antoni BenitoLaboratori d'Enginyeria de Proteïnes, Departament de Biologia, Facultat de Ciències, Universitat de Girona, Campus de Montilivi, C/Maria Aurèlia Capmany, 40, 17003 Girona, Spain.ORCID 0000-0002-9776-1003
Maria VilanovaLaboratori d'Enginyeria de Proteïnes, Departament de Biologia, Facultat de Ciències, Universitat de Girona, Campus de Montilivi, C/Maria Aurèlia Capmany, 40, 17003 Girona, Spain.ORCID 0000-0003-0523-815X
Universitat de Girona · ESInstitut Català d'Investigació Química · ESUniversitat Rovira i Virgili · ES

Funding

Generalitat de Catalunya, DGU SGR2014-70 and 2017 SGR 1720Ministerio de Economia y Competitividad (MINECO) Spain BIO2013-43517Universitat de Girona MPCUdG2016-18 and MPCUdG2016/048
6 · The paper itself

Abstract

A family of dinuclear iron (II) compounds with iminopyridine-based ligands displays selective cytotoxic activity against cancer cell lines. All compounds have IC

Indexed as

apoptosiscytotoxic mechanismdinuclear iron (II) compoundsiminopyridine ligandsinhibition of cell migrationselectivity for tumor cells

Identifiers

PMID36559294
PMCPMC9781652
OpenAlexW4311510808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.