Evidence map›Paper›PMID 36559281›Full record

ReviewPharmaceutics2022

Polysaccharide-Based Nanomedicines Targeting Lung Cancer.

Asif Ahmad Bhat, Gaurav Gupta, Khalid Saad Alharbi, Obaid Afzal, Abdulmalik S A Altamimi, Waleed Hassan Almalki, Imran Kazmi, Fahad A Al-Abbasi, Sami I Alzarea, Dinesh Kumar Chellappan and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 85 citations in OpenAlex.

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  16. Unwinding circular RNA's role in inflammatory pulmonary diseases.Naunyn-Schmiedeberg's archives of pharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 5 countries.

Asif Ahmad BhatSchool and of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Mahal Road, Jaipur 302017, India.
Gaurav GuptaSchool and of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Mahal Road, Jaipur 302017, India.
Khalid Saad AlharbiDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka 72388, Saudi Arabia.
Obaid AfzalDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al Kharj 11942, Saudi Arabia.ORCID 0000-0002-4188-5592
Abdulmalik S A AltamimiDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al Kharj 11942, Saudi Arabia.
Waleed Hassan AlmalkiDepartment of Pharmacology, College of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Imran KazmiDepartment of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0003-1881-5219
Fahad A Al-AbbasiDepartment of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Sami I AlzareaDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka 72388, Saudi Arabia.ORCID 0000-0003-4007-4023
Dinesh Kumar ChellappanDepartment of Life Sciences, School of Pharmacy, International Medical University, Bukit Jalil, Kuala Lumpur 57000, Malaysia.ORCID 0000-0001-5567-6663
Sachin Kumar SinghSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab 144411, India.
Ronan MacLoughlinResearch and Development, Science and Emerging Technologies, Aerogen, IDA Business Park, Dangan, H91 HE94 Galway, Ireland.ORCID 0000-0002-3164-1607
Brian G OliverSchool of Life Sciences, Faculty of Science, University of Technology, Sydney, NSW 2007, Australia.ORCID 0000-0002-7122-9262
Kamal DuaFaculty of Health, Australian Research Centre in Complementary and Integrative Medicine, University of Technology Sydney, Ultimo, NSW 2007, Australia.ORCID 0000-0002-7507-1159
Jouf University · SAKing Abdulaziz University · SAPrince Sattam Bin Abdulaziz University · SAUniversity of Technology Sydney · AUGyan Vihar University · INIMU University · MYLovely Professional University · INRoyal College of Surgeons in Ireland · IEUmm al-Qura University · SAUttaranchal University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A primary illness that accounts for a significant portion of fatalities worldwide is cancer. Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer around the globe. Radiation treatment, surgery, and chemotherapy are some medical procedures used in the traditional care of lung cancer. However, these methods lack selectivity and damage nearby healthy cells. Several polysaccharide-based nanomaterials have been created to transport chemotherapeutics to reduce harmful and adverse side effects and improve response during anti-tumour reactions. To address these drawbacks, a class of naturally occurring polymers called polysaccharides have special physical, chemical, and biological characteristics. They can interact with the immune system to induce a better immunological response. Furthermore, because of the flexibility of their structures, it is possible to create multifunctional nanocomposites with excellent stability and bioavailability for the delivery of medicines to tumour tissues. This study seeks to present new views on the use of polysaccharide-based chemotherapeutics and to highlight current developments in polysaccharide-based nanomedicines for lung cancer.

Indexed as

chemotherapyimmunitylung cancernanomedicinespolysaccharide

Identifiers

PMID36559281
PMCPMC9782996
OpenAlexW4311495040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.