Evidence map›Paper›PMID 36559198›Full record

ArticlePharmaceutics2022

Isopropyl Gallate, a Gallic Acid Derivative: In Silico and In Vitro Investigation of Its Effects on

Danielly Silva de Melo, José Arimatéa de Oliveira Nery Neto, Maisa de Sousa Dos Santos, Vinícius Duarte Pimentel, Rita de Cássia Viana Carvalho, Valéria Carlos de Sousa, Ruy Gabriel Costa Sousa, Lázaro Gomes do Nascimento, Michel Muálem de Moraes Alves, Daniel Dias Rufino Arcanjo and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Danielly Silva de MeloLaboratory of Antileishmanial Activity (LAA), Medicinal Plants Research Center, Federal University of Piauí, Teresina 64049-550, Piauí, Brazil.
José Arimatéa de Oliveira Nery NetoLaboratory of Antileishmanial Activity (LAA), Medicinal Plants Research Center, Federal University of Piauí, Teresina 64049-550, Piauí, Brazil.
Maisa de Sousa Dos SantosLaboratory of Antileishmanial Activity (LAA), Medicinal Plants Research Center, Federal University of Piauí, Teresina 64049-550, Piauí, Brazil.
Vinícius Duarte PimentelLaboratory of Antileishmanial Activity (LAA), Medicinal Plants Research Center, Federal University of Piauí, Teresina 64049-550, Piauí, Brazil.
Rita de Cássia Viana CarvalhoLaboratory of Antileishmanial Activity (LAA), Medicinal Plants Research Center, Federal University of Piauí, Teresina 64049-550, Piauí, Brazil.
Valéria Carlos de SousaLaboratory of Antileishmanial Activity (LAA), Medicinal Plants Research Center, Federal University of Piauí, Teresina 64049-550, Piauí, Brazil.
Ruy Gabriel Costa SousaLaboratory of Antileishmanial Activity (LAA), Medicinal Plants Research Center, Federal University of Piauí, Teresina 64049-550, Piauí, Brazil.
Lázaro Gomes do NascimentoLaboratory of Pharmaceutical Chemistry, Federal University of Paraíba, João Pessoa 58051-900, Paraíba, Brazil.
Michel Muálem de Moraes AlvesLaboratory of Antileishmanial Activity (LAA), Medicinal Plants Research Center, Federal University of Piauí, Teresina 64049-550, Piauí, Brazil.
Daniel Dias Rufino ArcanjoLaboratory of Antileishmanial Activity (LAA), Medicinal Plants Research Center, Federal University of Piauí, Teresina 64049-550, Piauí, Brazil.ORCID 0000-0001-7021-2744
Damião Pergentino de SousaLaboratory of Pharmaceutical Chemistry, Federal University of Paraíba, João Pessoa 58051-900, Paraíba, Brazil.
Fernando Aécio de Amorim CarvalhoLaboratory of Antileishmanial Activity (LAA), Medicinal Plants Research Center, Federal University of Piauí, Teresina 64049-550, Piauí, Brazil.
Universidade Federal do Piauí · BRUniversidade Federal da Paraíba · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isopropyl gallate (IPG) is a polyphenol obtained from alterations in the gallic acid molecule via acid catalysis with previously reported leishmanicidal and trypanocidal activities. The present study aims to evaluate in silico binding activity towards some targets for antileishmanial chemotherapy against

Indexed as

ADMETantileishmania activitymolecular dockingpolyphenolspropyl gallate

Identifiers

PMID36559198
PMCPMC9787715
OpenAlexW4311522313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.