Evidence map›Paper›PMID 36559131›Full record

ArticlePharmaceutics2022

Carvacrol and HP-β-Cyclodextrin Complexes: Extensive Characterization and Potential Cytotoxic Effect in Human Colorectal Carcinoma Cells.

María Isabel Rodríguez-López, María Teresa Mercader-Ros, Alfonso Pérez-Garrido, Horacio Pérez-Sánchez, José Antonio Pellicer, Carmen Lucas-Abellán, Silvia Montoro-García, María Josefa Yáñez-Gascón, Ángel Gil-Izquierdo, Estrella Núñez-Delicado and 1 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

María Isabel Rodríguez-LópezMolecular Recognition and Encapsulation Research Group (REM), Health Sciences Department, Universidad Católica de Murcia (UCAM), Campus de los Jerónimos 135, E-30107 Guadalupe, Spain.ORCID 0000-0003-3515-4950
María Teresa Mercader-RosMolecular Recognition and Encapsulation Research Group (REM), Health Sciences Department, Universidad Católica de Murcia (UCAM), Campus de los Jerónimos 135, E-30107 Guadalupe, Spain.
Alfonso Pérez-GarridoBioinformatics and High Performance Computing Group (BIO-HPC), Dpto. del Grado en Informática, Universidad Católica de Murcia (UCAM), Campus de los Jerónimos 135, E-30107 Guadalupe, Spain.
Horacio Pérez-SánchezBioinformatics and High Performance Computing Group (BIO-HPC), Dpto. del Grado en Informática, Universidad Católica de Murcia (UCAM), Campus de los Jerónimos 135, E-30107 Guadalupe, Spain.ORCID 0000-0003-4468-7898
José Antonio PellicerMolecular Recognition and Encapsulation Research Group (REM), Health Sciences Department, Universidad Católica de Murcia (UCAM), Campus de los Jerónimos 135, E-30107 Guadalupe, Spain.
Carmen Lucas-AbellánMolecular Recognition and Encapsulation Research Group (REM), Health Sciences Department, Universidad Católica de Murcia (UCAM), Campus de los Jerónimos 135, E-30107 Guadalupe, Spain.
Silvia Montoro-GarcíaCátedra de Riesgo Cardiovascular y Departamento de Nutrición, Facultad de Ciencias de la Salud, UCAM, Universidad Católica de Murcia (UCAM), Campus de los Jerónimos 135, E-30107 Guadalupe, Spain.ORCID 0000-0002-1948-1022
María Josefa Yáñez-GascónMolecular Recognition and Encapsulation Research Group (REM), Health Sciences Department, Universidad Católica de Murcia (UCAM), Campus de los Jerónimos 135, E-30107 Guadalupe, Spain.ORCID 0000-0001-8694-6072
Ángel Gil-IzquierdoResearch Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC, University Campus of Espinardo-Edif. 25, E-30100 Espinardo, Spain.ORCID 0000-0001-7646-0386
Estrella Núñez-DelicadoMolecular Recognition and Encapsulation Research Group (REM), Health Sciences Department, Universidad Católica de Murcia (UCAM), Campus de los Jerónimos 135, E-30107 Guadalupe, Spain.ORCID 0000-0002-0554-2365
José Antonio GabaldónMolecular Recognition and Encapsulation Research Group (REM), Health Sciences Department, Universidad Católica de Murcia (UCAM), Campus de los Jerónimos 135, E-30107 Guadalupe, Spain.ORCID 0000-0002-6649-2920

Funding

State Plan for Scientific and Technical Research and Innovation RTC-2015-3321-2
6 · The paper itself

Abstract

The aim of this study was to obtain solid carvacrol-cyclodextrin (CD) complexes for use in the pharmaceutical industry. To this end, the complexation of carvacrol at different pH values was studied in detail, to determine the type of CD and the reaction environment that supported the highest amount of encapsulated carvacrol. Evidence of the capability of hydroxypropyl-β-cyclodextrins (HP-β-CD) to form inclusion complexes with carvacrol (K

Indexed as

carvacrolcell viabilitychemical characterizationHP-β-cyclodextrinsmicrowave irradiationsolid complexes

Identifiers

PMID36559131
PMCPMC9786748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.