Evidence map›Paper›PMID 36559129›Full record

ReviewPharmaceutics2022

Progress on Thin Film Freezing Technology for Dry Powder Inhalation Formulations.

Sagar R Pardeshi, Eknath B Kole, Harshad S Kapare, Sachin M Chandankar, Prashant J Shinde, Ganesh S Boisa, Sanjana S Salgaonkar, Prabhanjan S Giram, Mahesh P More, Praveen Kolimi and 3 more

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
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  4. Outstanding Contributions to Aerosol Pulmonary Drug Delivery.Kona : powder science and technology in Japan · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sagar R PardeshiDepartment of Pharmaceutics, St. John Institute of Pharmacy and Research, Palghar 401404, India.ORCID 0000-0003-1359-5907
Eknath B KoleUniversity Institute of Chemical Technology, KBC North Maharashtra University, Jalgaon 425001, India.ORCID 0000-0002-0782-581X
Harshad S KapareDepartment of Pharmaceutics, Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pune 411018, India.ORCID 0000-0003-2991-7413
Sachin M ChandankarDepartment of Pharmaceutics, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur 425405, India.
Prashant J ShindeDepartment of Pharmaceutics, St. John Institute of Pharmacy and Research, Palghar 401404, India.
Ganesh S BoisaDepartment of Pharmaceutics, St. John Institute of Pharmacy and Research, Palghar 401404, India.
Sanjana S SalgaonkarDepartment of Pharmaceutics, St. John Institute of Pharmacy and Research, Palghar 401404, India.
Prabhanjan S GiramDepartment of Pharmaceutics, Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pune 411018, India.ORCID 0000-0003-0439-1347
Mahesh P MoreDepartment of Pharmaceutics, Dr. Rajendra Gode College of Pharmacy, Buldhana 443101, India.ORCID 0000-0002-2763-8560
Praveen KolimiDepartment of Pharmaceutics and Drug Delivery, University of Mississippi, Oxford, MS 38677, USA.
Dinesh NyavanandiProduct Development, Continuus Pharmaceuticals, 25 Olympia Ave, Woburn, MA 01801, USA.
Sathish DyawanapellyDepartment of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, NP Marg, Matunga, Mumbai 400019, India.ORCID 0000-0002-2310-1651
Vijayabhaskarreddy JunnuthulaDrug Research Program, Faculty of Pharmacy, University of Helsinki, Viikinkaari 5 E, 00790 Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The surface drying process is an important technology in the pharmaceutical, biomedical, and food industries. The final stage of formulation development (i.e., the drying process) faces several challenges, and overall mastering depends on the end step. The advent of new emerging technologies paved the way for commercialization. Thin film freezing (TFF) is a new emerging freeze-drying technique available for various treatment modalities in drug delivery. TFF has now been used for the commercialization of pharmaceuticals, food, and biopharmaceutical products. The present review highlights the fundamentals of TFF along with modulated techniques used for drying pharmaceuticals and biopharmaceuticals. Furthermore, we have covered various therapeutic applications of TFF technology in the development of nanoformulations, dry powder for inhalations and vaccines. TFF holds promise in delivering therapeutics for lung diseases such as fungal infection, bacterial infection, lung dysfunction, and pneumonia.

Indexed as

dry fine powderinhalationnovel drug deliverypoorly soluble drugpulmonarythin film freezing

Identifiers

PMID36559129
PMCPMC9784462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.