Evidence map›Paper›PMID 36558965›Full record

ReviewPharmaceuticals (Basel, Switzerland)2022

Vulvodynia: Pain Management Strategies.

Lucia Merlino, Luca Titi, Francesco Pugliese, Giulia D'Ovidio, Roberto Senatori, Carlo Della Rocca, Maria Grazia Piccioni

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Vulvodynia - A contemporary understanding and practical approach in primary care settings.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2024
    Review
  6. Immune mechanisms in vulvodynia: key roles for mast cells and fibroblasts.Frontiers in cellular and infection microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lucia MerlinoDepartment of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-4281-8308
Luca TitiDepartment of Anesthesia and Intensive Care Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Francesco PuglieseDepartment of Anesthesia and Intensive Care Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Giulia D'OvidioDepartment of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Roberto SenatoriItalian Society of Colposcopy and Cervicovaginal Pathology (SICPV), 00186 Rome, Italy.
Carlo Della RoccaDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 00161 Rome, Italy.
Maria Grazia PiccioniDepartment of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Sapienza University of Rome · ITSocietà Italiana di Cardiologia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vulvodynia is defined in this international consensus as persistent vulvar pain that occurs for >3 months without an identifiable cause and with several potential associated factors. At present there is no univocal consensus in the therapeutic treatment of vulvodynia. The methods of intervention are based on various aspects including, above all, the management of painful symptoms. Methods: a research on scientific database such as “Pubmed”, “Medline Plus”, “Medscape” was conducted, using the words “women’s genital pain” and “vulvodynia” for the review of the scientific evidence on the assessment and treatment of women’s genital pain. Results: Among the drugs with pain-relieving action, the most effective in the treatment of vulvodynia would seem to be those with antidepressant and anticonvulsant action, even if their mechanisms of action are not known and there are still insufficient studies able to demonstrate their real validity. Among the least effective are non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids. However, the ideal would seem to use a combined treatment with multiple types of drugs. Conclusions: Future studies are needed to draw up a unique therapeutic action plan that considers the stratification of patients with vulvodynia and the variability of the symptom.

Indexed as

chronic painpainpain treatmentvestibulodyniavulvodynia

Identifiers

PMID36558965
PMCPMC9781267
OpenAlexW4311529140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.