Evidence map›Paper›PMID 36558931›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Effect of Structural Differences in Naringenin, Prenylated Naringenin, and Their Derivatives on the Anti-Influenza Virus Activity and Cellular Uptake of Their Flavanones.

Ryosuke Morimoto, Chiaki Matsubara, Akari Hanada, Yuta Omoe, Tokutaro Ogata, Yuji Isegawa

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Anti-Influenza Virus Activity ofFoods (Basel, Switzerland) · 2023
    Review
  7. Antiproliferative Activity and Impact on Human Gut Microbiota of NewInternational journal of molecular sciences · 2023
    Article
  8. Prenylated Flavonoids with Selective Toxicity against Human Cancers.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ryosuke MorimotoDepartment of Food Sciences and Nutrition, Mukogawa Women's University, Nishinomiya 663-8558, Hyogo, Japan.
Chiaki MatsubaraDepartment of Food Sciences and Nutrition, Mukogawa Women's University, Nishinomiya 663-8558, Hyogo, Japan.
Akari HanadaDepartment of Food Sciences and Nutrition, Mukogawa Women's University, Nishinomiya 663-8558, Hyogo, Japan.
Yuta OmoeFaculty of Pharmaceutical Sciences, Hokuriku University, Kanazawa, 920-1181, Ishikawa, Japan.
Tokutaro OgataFaculty of Pharmaceutical Sciences, Hokuriku University, Kanazawa, 920-1181, Ishikawa, Japan.
Yuji IsegawaDepartment of Food Sciences and Nutrition, Mukogawa Women's University, Nishinomiya 663-8558, Hyogo, Japan.ORCID 0000-0001-9701-8431
Mukogawa Women's University · JPHokuriku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccines and antiviral drugs are widely used to treat influenza infection. However, they cannot rapidly respond to drug-resistant viruses. Therefore, new anti-influenza virus strategies are required. Naringenin is a flavonoid with potential for new antiviral strategies. In this study, we evaluated the antiviral effects of naringenin derivatives and examined the relationship between their cellular uptake and antiviral effects. Madin-Darby canine kidney (MDCK) cells were infected with the A/PR/8/34 strain and exposed to the compound-containing medium for 24 h. The amount of virus in the supernatant was calculated using focus-forming reduction assay. Antiviral activity was evaluated using IC

Indexed as

6-prenylnaringenin8-prenylnaringeninCitrullus lanatusflavanoneflavonoidnaringenin

Identifiers

PMID36558931
PMCPMC9785311
OpenAlexW4310213198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.