Evidence map›Paper›PMID 36558930›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Synthesis and Anti-Tumor Effects of Novel Pomalidomide Derivatives Containing Urea Moieties.

Yajie Guo, Xi Wang, Zhenzhen Wang, Longfei Mao, Jiahao Wang, Lizeng Peng, Guiqing Xu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Click Reactions in Medicinal Chemistry.Pharmaceuticals (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yajie GuoThe Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen 518033, China.
Xi WangSchool of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007, China.
Zhenzhen WangSchool of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007, China.
Longfei MaoSchool of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007, China.
Jiahao WangSchool of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007, China.
Lizeng PengKey Laboratory of Agro-Products Processing Technology of Shandong Province, Key Laboratory of Novel Food Resources Processing Ministry of Agriculture, Institute of Agro-Food Science and Technology Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Guiqing XuSchool of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007, China.
Henan Normal University · CNNankai University · CNShandong Academy of Agricultural Sciences · CNSun Yat-sen University · CN

Funding

Shenzhen Outbound Postdoctoral Research Grant CZBSHKYJJ002Shenzhen Science and Technology Program JCYJ20210324115208024
6 · The paper itself

Abstract

In order to explore novel immunomodulatory agents as anti-tumor drugs, we designed and synthesized a series of new pomalidomide derivatives containing urea moieties. Interestingly, in vitro biological experiments performed in several cancer cell lines showed that some of them displayed potent anti-tumor ability. These novel compounds

Indexed as

anti-tumor effectsimmunomodulatorypomalidomide derivativesurea moieties

Identifiers

PMID36558930
PMCPMC9785895
OpenAlexW4310243827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.