Evidence map›Paper›PMID 36558927›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

New 5-Aryl-1,3,4-Thiadiazole-Based Anticancer Agents: Design, Synthesis, In Vitro Biological Evaluation and In Vivo Radioactive Tracing Studies.

Rana M El-Masry, Basma M Essa, Adli A Selim, Soad Z El-Emam, Khaled O Mohamed, Tamer M Sakr, Hanan H Kadry, Azza T Taher, Sahar M Abou-Seri

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Rana M El-MasryOrganic Chemistry Department, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), October 6 City 12451, Egypt.ORCID 0000-0001-7280-1788
Basma M EssaRadioactive Isotopes and Generator Department, Hot Labs Center, Egyptian Atomic Energy Authority, P.O. Box 13759, Cairo 13759, Egypt.ORCID 0000-0002-3141-9918
Adli A SelimLabeled Compounds Department, Hot Labs Center, Egyptian Atomic Energy Authority, P.O. Box 13759, Cairo 13759, Egypt.ORCID 0000-0001-7095-5978
Soad Z El-EmamDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, October 6 University (O6U), October 6 City 12585, Egypt.ORCID 0000-0003-3712-4659
Khaled O MohamedDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo 11565, Egypt.ORCID 0000-0002-2293-5363
Tamer M SakrRadioactive Isotopes and Generator Department, Hot Labs Center, Egyptian Atomic Energy Authority, P.O. Box 13759, Cairo 13759, Egypt.ORCID 0000-0001-9162-5687
Hanan H KadryDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo 11565, Egypt.
Azza T TaherDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo 11565, Egypt.
Sahar M Abou-SeriDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo 11565, Egypt.
Cairo University · EGEgyptian Atomic Energy Authority · EGOctober 6 University · EGOctober University of Modern Sciences and Arts · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new series of 5-(4-chlorophenyl)-1,3,4-thiadiazole-based compounds featuring pyridinium (

Indexed as

1,3,4-thiadiazoleanticancer activityin vivo pharmacokineticsradiolabelingstructure-activity relationship

Identifiers

PMID36558927
PMCPMC9781117
OpenAlexW4310242060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.