Evidence map›Paper›PMID 36558910›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Protofibrillar Amyloid Beta Modulation of Recombinant hCaV2.2 (N-Type) Voltage-Gated Channels.

Eleni Kaisis, Laura J Thei, Gary J Stephens, Mark L Dallas

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eleni KaisisSchool of Pharmacy, University of Reading, Reading RG6 6UB, UK.
Laura J TheiSchool of Pharmacy, University of Reading, Reading RG6 6UB, UK.
Gary J StephensSchool of Pharmacy, University of Reading, Reading RG6 6UB, UK.ORCID 0000-0002-8966-4238
Mark L DallasSchool of Pharmacy, University of Reading, Reading RG6 6UB, UK.ORCID 0000-0002-5190-0522

Funding

Alzheimer's Association ARG- 16-440031
6 · The paper itself

Abstract

Cav2.2 channels are key regulators of presynaptic Ca

Indexed as

Alzheimer’s diseaseamyloid betaion channelneurodegenerationvoltage-gated calcium channel

Identifiers

PMID36558910
PMCPMC9783047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.