Evidence map›Paper›PMID 36558858›Full record

ArticlePathogens (Basel, Switzerland)2022

Low Risk of Occult Hepatitis B Infection among Vietnamese Blood Donors.

Tran Thanh Tung, Jürgen Schmid, Vu Xuan Nghia, Le Chi Cao, Le Thi Kieu Linh, Ikrormi Rungsung, Bui Tien Sy, Truong Nhat My, Nguyen Trong The, Nghiem Xuan Hoan and 7 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 3 countries.

Tran Thanh TungInstitute of Tropical Medicine, University of Tübingen, 72074 Tübingen, Germany.
Jürgen SchmidInstitute of Tropical Medicine, University of Tübingen, 72074 Tübingen, Germany.
Vu Xuan Nghia108 Military Central Hospital, Hanoi 10000, Vietnam.
Le Chi CaoInstitute of Tropical Medicine, University of Tübingen, 72074 Tübingen, Germany.ORCID 0000-0002-7817-4479
Le Thi Kieu LinhInstitute of Tropical Medicine, University of Tübingen, 72074 Tübingen, Germany.
Ikrormi RungsungInstitute of Tropical Medicine, University of Tübingen, 72074 Tübingen, Germany.
Bui Tien SyInstitute of Tropical Medicine, University of Tübingen, 72074 Tübingen, Germany.
Truong Nhat MyVietnamese-German Center for Medical Research (VG-CARE), Hanoi 10000, Vietnam.
Nguyen Trong TheVietnamese-German Center for Medical Research (VG-CARE), Hanoi 10000, Vietnam.ORCID 0000-0002-5433-7712
Nghiem Xuan HoanVietnamese-German Center for Medical Research (VG-CARE), Hanoi 10000, Vietnam.ORCID 0000-0002-6426-7818
Christian G MeyerInstitute of Tropical Medicine, University of Tübingen, 72074 Tübingen, Germany.ORCID 0000-0001-5561-2985
Heiner WedemeyerDepartment of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, 30623 Hannover, Germany.
Peter G KremsnerInstitute of Tropical Medicine, University of Tübingen, 72074 Tübingen, Germany.
Nguyen Linh ToanDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi 10000, Vietnam.
Le Huu SongVietnamese-German Center for Medical Research (VG-CARE), Hanoi 10000, Vietnam.
C-Thomas BockInstitute of Tropical Medicine, University of Tübingen, 72074 Tübingen, Germany.ORCID 0000-0002-2773-486X
Thirumalaisamy P VelavanInstitute of Tropical Medicine, University of Tübingen, 72074 Tübingen, Germany.
Vietnamese - German Center of Excellence in Medical Research · VN108 Military Central Hospital · VNUniversity of Tübingen · DECentre de Recherche Médicales de Lambaréné · GAHue University · VNMedizinische Hochschule Hannover · DERobert Koch Institute · DEVietnam Military Medical University · VN

Funding

Federal Ministry of Education and Research BMBF01DP19006AGerman Academic Exchange Service Project ID: 57592343Ministry of Science and Technology NDT/DE/21/07
6 · The paper itself

Abstract

Occult hepatitis B infection (OBI) is characterized by the presence of low levels of hepatitis B virus (HBV) DNA and undetectable HBsAg in the blood. The prevalence of OBI in blood donors in Asia ranges from 0.013% (China) to 10.9% (Laos), with no data available from Vietnam so far. We aimed to investigate the prevalence of OBI among Vietnamese blood donors. A total of 623 (114 women and 509 men) HBsAg-negative blood donors were screened for anti-HBc and anti-HBs by ELISA assays. In addition, DNA from sera was isolated and nested PCR was performed for the HBV surface gene (S); a fragment of the S gene was then sequenced in positive samples. The results revealed that 39% (

Indexed as

blood donorshepatitis B surface antigenhepatitis B virusoccult hepatitis BVietnam

Identifiers

PMID36558858
PMCPMC9786887
OpenAlexW4311232249

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.