Evidence map›Paper›PMID 36558844›Full record

ReviewPathogens (Basel, Switzerland)2022

HPV-Associated Breast Cancer: Myth or Fact?

Erik Kudela, Eva Kudelova, Erik Kozubík, Tomas Rokos, Terezia Pribulova, Veronika Holubekova, Kamil Biringer

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Erik KudelaClinic of Gynecology and Obstetrics, Jessenius Faculty of Medicine, Comenius University in Bratislava, 03601 Martin, Slovakia.
Eva KudelovaClinic of Surgery and Transplant Center, Jessenius Faculty of Medicine, Comenius University in Bratislava, 03601 Martin, Slovakia.
Erik KozubíkClinic of Gynecology and Obstetrics, Jessenius Faculty of Medicine, Comenius University in Bratislava, 03601 Martin, Slovakia.
Tomas RokosClinic of Gynecology and Obstetrics, Jessenius Faculty of Medicine, Comenius University in Bratislava, 03601 Martin, Slovakia.ORCID 0000-0003-4585-9671
Terezia PribulovaClinic of Gynecology and Obstetrics, Jessenius Faculty of Medicine, Comenius University in Bratislava, 03601 Martin, Slovakia.
Veronika HolubekovaBiomedical Center Martin, Jessenius Faculty of Medicine, Comenius University in Bratislava, 03601 Martin, Slovakia.ORCID 0000-0002-5979-8358
Kamil BiringerClinic of Gynecology and Obstetrics, Jessenius Faculty of Medicine, Comenius University in Bratislava, 03601 Martin, Slovakia.ORCID 0000-0002-3471-0508

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some estimates place the proportion of human malignancies attributable to viruses at between 15 and 20 percent. Viruses including the human papillomavirus are considered an interesting but controversial etiological risk factor for breast cancer. HPV infection is anticipated to be an early trigger in breast cancer carcinogenesis, followed by cumulative alterations over time ("hit and run" mechanism) through synergy with other environmental factors. The association between HPV and breast cancer has not yet been verified. There are very conflicting data on the presence of HPV DNA in breast cancer samples, and we lack a clarified, exact mode of HPV transmission to the breast. In our review article we analyzed the up-to-date knowledge about the association of HPV and breast cancer. Furthermore, we summarized the available original research published since 2010. In conclusion, the complexity and inconsistency of the available results together with the relatively low prevalence of HPV infection requires extensive research with much larger studies and exact and unified diagnostic methods are required to better understand the role of the HPV in breast carcinogenesis.

Indexed as

breast cancercarcinogenesishuman papillomavirusoncogene

Identifiers

PMID36558844
PMCPMC9786769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.