Evidence map›Paper›PMID 36558843›Full record

ArticlePathogens (Basel, Switzerland)2022

Molecular Diagnosis of Encephalitis/Meningoencephalitis Caused by Free-Living Amoebae from a Tertiary Center in India.

Sumeeta Khurana, Chayan Sharma, Bishan Dass Radotra, Abhishek Mewara, Parveen Tanwar, Priya Datta, Rakesh Sehgal

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Free-living amoebae.Tropical parasitology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sumeeta KhuranaDepartment of Medical Parasitology, Postgraduate Institute of Medical Education & Research, Chandigarh 160012, India.ORCID 0000-0002-6004-6292
Chayan SharmaDepartment of Medical Parasitology, Postgraduate Institute of Medical Education & Research, Chandigarh 160012, India.ORCID 0000-0001-9802-2774
Bishan Dass RadotraDepartment of Histopathology, Postgraduate Institute of Medical Education & Research, Chandigarh 160012, India.
Abhishek MewaraDepartment of Medical Parasitology, Postgraduate Institute of Medical Education & Research, Chandigarh 160012, India.
Parveen TanwarDepartment of Medical Parasitology, Postgraduate Institute of Medical Education & Research, Chandigarh 160012, India.
Priya DattaDepartment of Medical Parasitology, Postgraduate Institute of Medical Education & Research, Chandigarh 160012, India.
Rakesh SehgalDepartment of Medical Parasitology, Postgraduate Institute of Medical Education & Research, Chandigarh 160012, India.ORCID 0000-0003-2910-4973
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPathogenic free-living amoeba (FLA) such as

methodsThis study included samples from 156 patients with suspected encephalitis/meningoencephalitis, including 149 cerebrospinal fluid (CSF) samples, 5 brain tissue biopsies, and 2 brain abscess samples. All the samples were subjected to PCR-based detection of

resultsWe detected 11 samples positive for FLA, including 6

conclusionsThe PCR-based detection of FLA in patients suspected of encephalitis/meningoencephalitis was found to be fast, efficient, and reliable in our study. We suggest the use of these PCRs in laboratories to obtain additional data on their efficiency in diagnosing FLA infections of the CNS. The present study was conducted with a small sample size of 156 patient samples, and we found only six

Indexed as

AcanthamoebaBalamuthiacentral nervous systemencephalitisfree-living amoebameningitisNaegleria

Identifiers

PMID36558843
PMCPMC9783764
OpenAlexW4312124151

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.