Evidence map›Paper›PMID 36558789›Full record

ReviewPathogens (Basel, Switzerland)2022

Towards a Harmonized Terminology: A Glossary for Biocide Susceptibility Testing.

Szilvia Neuhaus, Andrea T Feßler, Ralf Dieckmann, Lara Thieme, Mathias W Pletz, Stefan Schwarz, Sascha Al Dahouk

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. When Disinfection Fails: Biocide Tolerance as a Driver ofAntibiotics (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Review
  6. Biocide resistance inInfection prevention in practice · 2024
    Review
  7. Biocide Susceptibility and Antimicrobial Resistance ofAntibiotics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Szilvia NeuhausGerman Federal Institute for Risk Assessment, 10589 Berlin, Germany.
Andrea T FeßlerCentre for Infection Medicine, Department of Veterinary Medicine, Institute of Microbiology and Epizootics, Freie Universität Berlin, 14163 Berlin, Germany.
Ralf DieckmannGerman Federal Institute for Risk Assessment, 10589 Berlin, Germany.ORCID 0000-0002-1533-7496
Lara ThiemeInstitute of Infectious Diseases and Infection Control, Jena University Hospital, Friedrich-Schiller-University Jena, 07747 Jena, Germany.
Mathias W PletzInstitute of Infectious Diseases and Infection Control, Jena University Hospital, Friedrich-Schiller-University Jena, 07747 Jena, Germany.ORCID 0000-0001-8157-2753
Stefan SchwarzCentre for Infection Medicine, Department of Veterinary Medicine, Institute of Microbiology and Epizootics, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0002-6303-8212
Sascha Al DahoukGerman Federal Institute for Risk Assessment, 10589 Berlin, Germany.ORCID 0000-0003-3835-0818
Federal Institute for Risk Assessment · DEFreie Universität Berlin · DEJena University Hospital · DE

Funding

Federal Ministry for Education and Research 01KI2009DFederal Ministry of Education and Research 01KI1907
6 · The paper itself

Abstract

Disinfection is a key strategy to reduce the burden of infections. The contact of bacteria to biocides-the active substances of disinfectants-has been linked to bacterial adaptation and the development of antimicrobial resistance. Currently, there is no scientific consensus on whether the excessive use of biocides contributes to the emergence and spread of multidrug resistant bacteria. The comprehensive analysis of available data remains a challenge because neither uniform test procedures nor standardized interpretive criteria nor harmonized terms are available to describe altered bacterial susceptibility to biocides. In our review, we investigated the variety of criteria and the diversity of terms applied to interpret findings in original studies performing biocide susceptibility testing (BST) of field isolates. An additional analysis of reviews summarizing the knowledge of individual studies on altered biocide susceptibility provided insights into currently available broader concepts for data interpretation. Both approaches pointed out the urgent need for standardization. We, therefore, propose that the well-established and approved concepts for interpretation of antimicrobial susceptibility testing data should serve as a role model to evaluate biocide resistance mechanisms on a single cell level. Furthermore, we emphasize the adaptations necessary to acknowledge the specific needs for the evaluation of BST data. Our approach might help to increase scientific awareness and acceptance.

Indexed as

antimicrobial resistancebiocide resistancebiocide susceptibility testingbiocide tolerance

Identifiers

PMID36558789
PMCPMC9780826
OpenAlexW4311100508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.