Evidence map›Paper›PMID 36558775›Full record

ArticlePathogens (Basel, Switzerland)2022

Assessment of the Susceptibility of Clinical Gram-Negative and Gram-Positive Bacterial Strains to Fosfomycin and Significance of This Antibiotic in Infection Treatment.

Beata Kowalska-Krochmal, Beata Mączyńska, Danuta Rurańska-Smutnicka, Anna Secewicz, Grzegorz Krochmal, Małgorzata Bartelak, Aleksandra Górzyńska, Klaudyna Laufer, Krystyna Woronowicz, Joanna Łubniewska and 3 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Beata Kowalska-KrochmalDepartment of Pharmaceutical Microbiology and Parasitology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.ORCID 0000-0002-1224-1560
Beata MączyńskaDepartment of Pharmaceutical Microbiology and Parasitology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.ORCID 0000-0001-6388-7970
Danuta Rurańska-SmutnickaDepartment of Pharmaceutical Microbiology and Parasitology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.
Anna SecewiczDepartment of Pharmaceutical Microbiology and Parasitology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.
Grzegorz KrochmalDepartment of Pharmaceutical Microbiology and Parasitology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.
Małgorzata BartelakDepartment of Pharmaceutical Microbiology and Parasitology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.
Aleksandra GórzyńskaDepartment of Pharmaceutical Microbiology and Parasitology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.
Klaudyna LauferDepartment of Laboratory Diagnostics, Jan Mikulicz-Radecki University Teaching Hospital, Borowska 213, 50-556 Wrocław, Poland.
Krystyna WoronowiczSynevo, T. Marciniak Lower Silesian Specialized Hospital, Gen. A. E. Fieldorfa 2, 54-049 Wrocław, Poland.
Joanna ŁubniewskaMicrobiological Laboratory, Provincial Specialized Hospital in Legnica, Iwaszkiewicza 5, 59-220 Legnica, Poland.
Jolanta ŁappoMicrobiological Laboratory, A. Sokolowski Specialized Hospital in Walbrzych, Health Department in Klodzko, A. Sokołowskiego 4, 58-309 Walbrzych, Poland.
Magdalena CzwartosBacteriology Laboratory, Provincial Specialized Hospital in Klodzko, Szpitalna 1A, 57-300 Klodzko, Poland.
Ruth Dudek-WicherDepartment of Pharmaceutical Microbiology and Parasitology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.
Wroclaw Medical University · PLWitelon State University of Applied Sciences in Legnica · PL

Funding

Wrocław Medical University SUBZ.D230.22.026
6 · The paper itself

Abstract

Multidrug resistance of bacteria has prompted intensive development work on new medicines, but also the search for effective options among the oldest antibiotics. Although intravenous fosfomycin (IVFOS) seems to be an interesting proposal, the recommended agar dilution method for susceptibility determination poses a major problem in routine diagnostic testing. As a consequence, there is a lack of comprehensive data on the frequency of isolation of susceptible or resistant strains. This fact triggered the disposition of EUCAST concerning the revision of IVFOS breakpoints (BPs), including withdrawal of BPs for

Indexed as

agar dilution methodGram-positive and Gram-negative strainsin vitro susceptibilityIV fosfomycinmultidrug-resistant strains

Identifiers

PMID36558775
PMCPMC9786176
OpenAlexW4311002448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.