ArticleNutrients2022
The Effect of Breast Milk Microbiota on the Composition of Infant Gut Microbiota: A Cohort Study.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Difference in the Intestinal Microbiota between Breastfeed Infants and Infants Fed with Artificial Milk: A Systematic Review.Pathogens (Basel, Switzerland) · 2024Pooled it
- Prevalence and risk factors of recurrent respiratory tract infections in preschool children: a systematic review and meta-analysis.Jornal de pediatria · 2026Review
- Clostridium Abundance and Lower Weight-for-AgeJMIR pediatrics and parenting · 2026Article
- Article
- Temporal dynamics and functional maturation of the infant gut microbiota during the first year of life.BMC microbiology · 2026Article
- A Metagenomic Comparison of the Colostrum Microbiome in Bulgarian Mothers by Delivery Mode: A Pilot Study.Microorganisms · 2026Article
- Human milk microbiota: origins, determinants, and roles in maternal-infant microbial transmission and infant microbiome assembly.Frontiers in microbiology · 2026Review
- The influence of breast milk microbiota from HIV-infected women on infant gut microbiota colonization within the first two weeks of life.Frontiers in microbiomes · 2026Article
- Association of feeding methods in early life with gut microbiota in neonates.Frontiers in microbiology · 2026Article
- Distinct patterns and interactions of microbiota and short-chain fatty acids in breast milk and infant gut from rural and urban dyads.Frontiers in microbiology · 2026Article
- Exploring the role of intelectin-1 in modulating asthma through the gut-bone-lung axis.Gut microbes · 2025Article
- Assembly of the infant gut microbiome and resistome are linked to bacterial strains in mother's milk.Nature communications · 2025Article
- Factors Influencing the Colostrum's Microbiota: A Systematic Review of the Literature.Children (Basel, Switzerland) · 2025Review
- Long-Term Breastfeeding: Protective Effects Against Triple-Negative Breast Cancer and the Role of the Breast Microbiota.Pathogens (Basel, Switzerland) · 2025Review
- Infant gut microbiota and SCFAs mediate the association between early-life human milk microbiota and neurodevelopment.NPJ biofilms and microbiomes · 2025Article
- The association between short-term postoperative complications and bowel function after surgery for Hirschsprung disease.BMC pediatrics · 2025Article
- Role of maternal milk in providing a healthy intestinal microbiome for the preterm neonate.Pediatric research · 2025Review
- Breastfeeding Shapes the Gut Microbiota and Its Structure Is Associated with Weight Gain Trajectories in Mexican Infants.Nutrients · 2025Article
- Gut phages and their interactions with bacterial and mammalian hosts.Journal of bacteriology · 2025Review
- Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Evidence shows that breast milk microbiota and an infant’s gut microbiota are related. This study aimed to compare the effects of breast milk microbiota on the construction and colonization of gut microbiota in newborns. In this study, 23 healthy infants were selected and divided into a breastfeeding group (13) and a mixed feeding group (10) based on the feeding method within one month of age. Infant fecal and breast milk samples were collected on the day of birth (0 day) and 30 days after birth (30 days) for 16S rRNA second-generation sequencing and SCFA detection. The results showed that Firmicutes and Actinobacteriota on day 0 and Firmicutes and Proteobacteria on 30 d dominated breast milk gut microbiota. There were correlations between the breast milk microbiota and the infant gut microbiota in each group (p < 0.05). Additionally, breast milk microbiota correlated more significantly with infants’ SCFAs in the breastfeeding group than in the mixed feeding group. This study showed that breast milk microbiota partially influences the construction of infant gut microbiota, with some key strains having a crucial influence, such as Lactobacillus, Bifidobacterium, and Enterobacter. However, the effect of breast milk microbiota on infant gut microbiota is not through direct strain transmission but has been indirectly influenced, which may be related to the cross-feeding effect mediated by SCFAs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.