Evidence map›Paper›PMID 36558549›Full record

ArticleNutrients2022

Chebulic Acid Prevents Hypoxia Insult via Nrf2/ARE Pathway in Ischemic Stroke.

Rong Zhou, Kuan Lin, Changlong Leng, Mei Zhou, Jing Zhang, Youwei Li, Yujing Liu, Xiansheng Ye, Xiaoli Xu, Binlian Sun and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Effects of DietaryAnimals : an open access journal from MDPI · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Rong ZhouWuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China.
Kuan LinWuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China.ORCID 0000-0002-9458-032X
Changlong LengWuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China.
Mei ZhouWuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China.
Jing ZhangWuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China.
Youwei LiWuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China.
Yujing LiuWuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China.
Xiansheng YeWuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China.
Xiaoli XuWuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China.
Binlian SunWuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China.
Xiji ShuWuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China.
Wei LiuWuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China.
Jianghan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excessive reactive oxygen species (ROS) production contributes to brain ischemia/reperfusion (I/R) injury through many mechanisms including inflammation, apoptosis, and cellular necrosis. Chebulic acid (CA) isolated from

Indexed as

Ischemic StrokeNeuroblastomaReperfusion InjuryAnimalsAntioxidantsApoptosisBenzopyransGlucoseHumansHypoxiaMiceNF-E2-Related Factor 2Oxidative StressReactive Oxygen SpeciesSignal TransductionAntioxidantsBenzopyranschebulic acidGlucoseNF-E2-Related Factor 2Reactive Oxygen SpeciesantioxidantsChebulic acidischemic strokeneuroprotectionNrf2

Identifiers

PMID36558549
PMCPMC9781341
OpenAlexW4312196106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.