Evidence map›Paper›PMID 36558547›Full record

ArticleNutrients2022

Examining the Composition of the Oral Microbiota as a Tool to Identify Responders to Dietary Changes.

Kirstin Vach, Ali Al-Ahmad, Annette Anderson, Johan Peter Woelber, Lamprini Karygianni, Annette Wittmer, Elmar Hellwig

Abstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kirstin VachDepartment of Operative Dentistry and Periodontology, Center for Dental Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Hugstetter Straße 55, D-79106 Freiburg, Germany.ORCID 0000-0001-9278-2203
Ali Al-AhmadDepartment of Operative Dentistry and Periodontology, Center for Dental Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Hugstetter Straße 55, D-79106 Freiburg, Germany.ORCID 0000-0001-8769-599X
Annette AndersonDepartment of Operative Dentistry and Periodontology, Center for Dental Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Hugstetter Straße 55, D-79106 Freiburg, Germany.ORCID 0000-0002-4489-1939
Johan Peter WoelberDepartment of Operative Dentistry and Periodontology, Center for Dental Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Hugstetter Straße 55, D-79106 Freiburg, Germany.ORCID 0000-0003-0921-4630
Lamprini KarygianniClinic for Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, CH-8032 Zurich, Switzerland.ORCID 0000-0002-7893-0393
Annette WittmerDepartment of Medical Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, Faculty of Medicine and Medical Center, University of Freiburg, Hermann-Herder-Straße 11, D-79104 Freiburg, Germany.
Elmar HellwigDepartment of Operative Dentistry and Periodontology, Center for Dental Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Hugstetter Straße 55, D-79106 Freiburg, Germany.

Funding

Deutsche Forschungsgemeinschaft DFG, AL-1179/2-1
6 · The paper itself

Abstract

backgroundThe role of diet and nutrition in the prevention of oral diseases has recently gained increasing attention. Understanding the influence of diet on oral microbiota is essential for developing meaningful prevention approaches to oral diseases, and the identification of typical and atypical responders may contribute to this.

methodsWe used data from an experimental clinical study in which 11 participants were exposed to different dietary regimens in five consecutive phases. To analyse the influence of additional nutritional components, we examined changes in bacterial concentrations measured by culture techniques compared to a run-in phase. A measure of correspondence between the mean and individual patterns of the bacterial composition is introduced.

resultsThe distance measures introduced showed clear differences between the subjects. In our data, two typical and three atypical responders appear to have been identified.

conclusionsThe proposed method is suitable to identify typical and atypical responders, even in small datasets. We recommend routinely performing such analyses.

Indexed as

MicrobiotaBacteriaDietHumansNutritional Statuscompositional datamicrobiomenutritionoral healthresponder

Identifiers

PMID36558547
PMCPMC9780922

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.