Evidence map›Paper›PMID 36558522›Full record

ArticleNutrients2022

Influence of Nutritional Parameters on the Evolution, Severity and Prognosis of Critically Ill Patients with COVID-19.

Yenifer Gamarra-Morales, Jorge Molina-López, Juan Francisco Machado-Casas, Lourdes Herrera-Quintana, Héctor Vázquez-Lorente, José Castaño-Pérez, José Miguel Perez-Villares, Elena Planells

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yenifer Gamarra-MoralesClinical Analysis Unit, Valle de los Pedroches Hospital, Pozoblanco, 14400 Córdoba, Spain.ORCID 0000-0003-0921-2168
Jorge Molina-LópezFaculty of Education, Psychology and Sports Sciences, University of Huelva, 21007 Huelva, Spain.ORCID 0000-0003-2516-5226
Juan Francisco Machado-CasasIntensive Care Unit, Virgen de las Nieves Hospital, Fuerzas Armadas Avenue, 18014 Granada, Spain.ORCID 0000-0001-7852-6553
Lourdes Herrera-QuintanaDepartment of Physiology, Faculty of Pharmacy, Institute of Nutrition and Food Technology "José Mataix", University of Granada, 18071 Granada, Spain.ORCID 0000-0003-1407-322X
Héctor Vázquez-LorenteDepartment of Physiology, Faculty of Pharmacy, Institute of Nutrition and Food Technology "José Mataix", University of Granada, 18071 Granada, Spain.ORCID 0000-0003-0183-6902
José Castaño-PérezIntensive Care Unit, Virgen de las Nieves Hospital, Fuerzas Armadas Avenue, 18014 Granada, Spain.
José Miguel Perez-VillaresIntensive Care Unit, Virgen de las Nieves Hospital, Fuerzas Armadas Avenue, 18014 Granada, Spain.
Elena PlanellsDepartment of Physiology, Faculty of Pharmacy, Institute of Nutrition and Food Technology "José Mataix", University of Granada, 18071 Granada, Spain.
Hospital Universitario Virgen de las Nieves · ESUniversidad de Granada · ESHospital San Pedro · ESUniversidad de Huelva · ES

Funding

European Regional Development Fund (ERDF) Andalucía REF. A-CTS-708-UGR20Instituto de Salud Carlos III Project FIS PI10/1993
6 · The paper itself

Abstract

This study evaluated the clinical and nutritional status, the evolution over three days, and the relationship between nutritional, inflammatory, and clinical parameters of critically ill patients with COVID-19. A longitudinal study was conducted in the Intensive Care Unit of the Virgen de las Nieves University Hospital in Granada (Spain). The study population comprised patients with a positive polymerase chain reaction test for COVID-19 presenting critical clinical involvement. Clinical outcomes were collected, and inflammatory and nutritional parameters (albumin, prealbumin, transferrin, transferrin saturation index, cholesterol, triglycerides and Controlling Nutritional Status (CONUT) score) were determined. A total of 202 critical patients with COVID-19 were selected, presenting highly altered clinical-nutritional parameters. The evolution experienced by the patients on the third day of admission was a decrease in albumin (p < 0.001) and an increase in prealbumin (p < 0.001), transferrin (p < 0.002), transferrin saturation index (p < 0.018), and cholesterol (p < 0.001). Low levels of albumin, prealbumin (on the third day) and high CONUT score (on the third day) showed an association with higher mortality. Nutritional variables were inversely correlated with clinical and inflammatory parameters. Critically ill patients with COVID-19 have poor nutritional status related to a poor prognosis of disease severity and mortality.

Indexed as

COVID-19PrealbuminAlbuminsCritical IllnessHumansLongitudinal StudiesNutritional StatusPrognosisRetrospective StudiesTransferrinAlbuminsPrealbuminTransferrinCOVID-19morbiditymortalitynutritional biomarkersnutritional status

Identifiers

PMID36558522
PMCPMC9783074
OpenAlexW4312195409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.