Evidence map›Paper›PMID 36558509›Full record

ArticleNutrients2022

Assessment of Vitamin D Status in Slovenian Premenopausal and Postmenopausal Women, Using Total, Free, and Bioavailable 25-Hydroxyvitamin D (25(OH)D).

Vid Vičič, Andreja Kukec, Saša Kugler, Ksenija Geršak, Joško Osredkar, Ruža Pandel Mikuš

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Vid VičičFaculty of Health Sciences, Chair of Biomedicine in Healthcare, University of Ljubljana, Zdravstvena pot 5, 1000 Ljubljana, Slovenia.
Andreja KukecNational Institute of Public Health, Trubarjeva 2, 1000 Ljubljana, Slovenia.
Saša KuglerNational Institute of Public Health, Trubarjeva 2, 1000 Ljubljana, Slovenia.
Ksenija GeršakFaculty of Medicine, Division of Obstetrics and Gynaecology, University of Ljubljana, Šlajmerjeva 3, 1000 Ljubljana, Slovenia.ORCID 0000-0001-9088-2382
Joško OsredkarInstitute of Clinical Chemistry and Biochemistry, University Medical Centre Ljubljana, Njegoševa 4, 1000 Ljubljana, Slovenia.ORCID 0000-0002-1839-2415
Ruža Pandel MikušFaculty of Health Sciences, Chair of Biomedicine in Healthcare, University of Ljubljana, Zdravstvena pot 5, 1000 Ljubljana, Slovenia.
University of Ljubljana · SINational Institute of Public Health · SI

Funding

Slovenian Research Agency No. P3-0429
6 · The paper itself

Abstract

The objective of our study was to evaluate vitamin D status and its predictors in Slovenian premenopausal and postmenopausal women. A cross-sectional study was carried out between 1 March 2021 and 31 May 2021. A total of 319 healthy women from the Central Slovenian region aged between 44 and 65 were recruited; 176 were included in the final analysis. The vitamin D status was determined by measuring the total 25-Hydroxycholecalciferol (25(OH)D) concentration, vitamin D binding protein (DBP), and albumin and calculating the bioavailable 25(OH)D and free 25(OH)D. For the calculation of bioavailable and free 25(OH)D, we developed a new online calculator. The Endocrine Society’s thresholds for vitamin D deficiency and insufficiency were used; 29.0% of premenopausal and 24.4% of postmenopausal subjects were found to be vitamin D deficient (total 25(OH)D < 50 nmol/L); 76.8% of the premenopausal and 61.7% of postmenopausal subjects were found to have insufficient levels (total 25(OH)D < 75 nmol/L). Premenopausal women had 11.8% lower total 25(OH)D, 32.2% lower bioavailable 25(OH)D, and 25.2% higher DBP than postmenopausal women. The most important predictors of vitamin D status were vitamin D supplementation and time spent in the sun. Contrary to similar studies, the vitamin D status in Slovenian postmenopausal women was significantly better than in premenopausal women. In postmenopausal women, the measurement of free or bioavailable 25(OH)D instead of the total 25(OH)D could be advantageous.

Indexed as

CalcifediolVitamin D DeficiencyAdultAgedCross-Sectional StudiesFemaleHumansMiddle AgedPostmenopauseVitamin DVitamin D-Binding ProteinVitamins25-hydroxyvitamin DCalcifediolVitamin DVitamin D-Binding ProteinVitamins25(OH)Dbioavailable 25(OH)DcalcidiolcholecalciferolDBPfree 25(OH)Dmenopauseonline calculatorpostmenopausalpremenopausalvitamin D

Identifiers

PMID36558509
PMCPMC9784017
OpenAlexW4312194618

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.