ArticleNutrients2022
Ideal Cardiovascular Health Metrics Are Associated with Reduced Severity of Hepatic Steatosis and Liver Fibrosis Detected by Transient Elastography.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Association of Life's Simple 7 with metabolic-associated steatotic liver disease and non-invasive fibrosis markers.Open heart · 2026Article
- Dietary niacin intake and mortality outcomes in hypertensive populations: analysis from NHANES 2003-2016.Journal of health, population, and nutrition · 2025Article
- Cardiovascular Health Trajectories and Prevalent Metabolic Dysfunction-Associated Steatotic Liver Disease in Midlife: The CARDIA Study.Journal of the American Heart Association · 2025Article
- Life's Crucial 9 and NAFLD from association to SHAP-interpreted machine learning predictions.Scientific reports · 2025Article
- Association of Life's Essential 8 and Life's Simple 7 with metabolic-associated fatty liver disease in the United States.World journal of hepatology · 2025Article
- The association of dietary nutrients consumption with hepatic steatosis and fibrosis from NHANES 2017-2020.Frontiers in nutrition · 2025Article
- Cumulative exposure to AHA Life's Essential 8 is associated with nonalcoholic fatty liver disease: a large cohort study.Nutrition & metabolism · 2024Article
- Article
- Association of cardiovascular health and educational status in a screening cohort.Central European journal of public health · 2024Article
- Associations of life's essential 8 with MAFLD and liver fibrosis among US adults: a nationwide cross-section study.Frontiers in nutrition · 2024Article
- Association between dietary niacin intake and cognitive function in the elderly: Evidence from NHANES 2011-2014.Food science & nutrition · 2023Article
- Geriatric nutrition risk index in the prediction of all-cause and cardiovascular mortality in elderly hypertensive population: NHANES 1999-2016.Frontiers in cardiovascular medicine · 2023Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
Life's Simple 7 (LS7) is the American Heart Association's (AHA) proposal for a healthy lifestyle, also known as cardiovascular health (CVH) metrics. However, the association between CVH metrics and the severity of hepatic steatosis and liver fibrosis detected by transient elastography is unknown. We performed a cross-sectional study using the data from the 2017-2018 National Health and Nutrition Examination Survey (NHANES) cycle. The controlled attenuation parameter (CAP) and liver stiffness measurement (LSM) were used to evaluate the severity of hepatic steatosis and liver fibrosis and to define NAFLD, advanced liver fibrosis, and cirrhosis. A total of 2679 participants were included. Multivariate linear regression analysis revealed that per 1-unit increase in the CVH metric, CAP and LSM decreased by 8.565 units and 0.274 units, respectively. In the multivariate logistic regression analysis, the risk of NAFLD, advanced liver fibrosis, and cirrhosis were 7, 10, and 6 times higher in the poor CVH group than in the ideal CVH group. Subgroup analysis indicated that CVD patients and non-Hispanic whites could benefit more from ideal CVH. In conclusion, adherence to ideal CVH metrics, as proposed by the AHA, can significantly reduce the risk of hepatic steatosis and liver fibrosis.
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Registered trials
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