Evidence map›Paper›PMID 36558437›Full record

ArticleNutrients2022

The Bioavailability of Glycyrrhizinic Acid Was Enhanced by Probiotic

Huifang Li, Jing Wang, Yifan Fu, Ke Zhu, Zhiling Dong, Jinjun Shan, Liuqing Di, Shu Jiang, Tianjie Yuan

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Huifang LiSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Jing WangSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Yifan FuSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Ke ZhuSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Zhiling DongSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Jinjun ShanJiangsu Key Laboratory of Pediatric Respiratory Disease, Nanjing University of Chinese Medicine, Nanjing 210023, China.ORCID 0000-0001-8079-7950
Liuqing DiSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Shu JiangSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Tianjie YuanSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.ORCID 0000-0002-1043-9514
Nanjing University of Chinese Medicine · CN

Funding

Jiangsu Provincial Postgraduate Research and Practice Innovation Program SJCX21_0682National Natural Science Foundation of China No.81703396, 82074126Natural Science Foundation Youth Project of Nanjing University of Chinese Medicine NZY81703396
6 · The paper itself

Abstract

Glycyrrhizinic acid (GL) is clinically applied to treat liver injury, and the bioavailability of orally administered GL is closely related to the gut microbiota. Therefore, the dysbiosis of gut flora in liver injury could significantly influence GL bioavailability. Still, less is known about the impact of probiotic supplementation on the bio-absorption process of oral medication, especially under a pathological state. Herein, probiotic

Indexed as

Lacticaseibacillus rhamnosusProbioticsAnimalsBiological AvailabilityDietary SupplementsGlycyrrhizic AcidLiver CirrhosisRatsGlycyrrhizic Acidbioavailabilityglycyrrhizinic acidgut microbiotaoral drugsprobiotics

Identifiers

PMID36558437
PMCPMC9782010
OpenAlexW4312126202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.