Evidence map›Paper›PMID 36558429›Full record

ReviewNutrients2022

Potential Role of Bioactive Proteins and Peptides Derived from Legumes towards Metabolic Syndrome.

Marta Garcés-Rimón, Diego Morales, Marta Miguel-Castro

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Timbe (Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  12. Review
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Marta Garcés-RimónGrupo de Biotecnología Alimentaria, Universidad Francisco de Vitoria, 28223 Madrid, Spain.ORCID 0000-0002-3888-4150
Diego MoralesNutrigenomics Research Group, Department of Biochemistry and Biotechnology, Universitat Rovira i Virgili, 43007 Tarragona, Spain.ORCID 0000-0002-4600-6673
Marta Miguel-CastroInstitute of Food Science Research-CIAL (UAM+CSIC), C/Nicolas Cabrera 9, Campus de Cantoblanco, Universidad Autónoma de Madrid, 28049 Madrid, Spain.ORCID 0000-0002-5525-1056
Instituto de Investigación en Ciencias de la Alimentación · ESUniversidad Francisco de Vitoria · ESUniversitat Rovira i Virgili · ES

Funding

Francisco de Vitoria University UFV 2019-09Spanish Ministry of Education, Science and Universities AGL2017-89213
6 · The paper itself

Abstract

Legumes have been widely consumed and used to isolate bioactive compounds, mainly proteins. The aim of this study was to review the beneficial actions of different legumes proteins and peptides updating the main findings that correlate legumes consumption and the effects on non-transmissible chronic diseases, specifically metabolic syndrome. An exhaustive revision of five relevant bioactivities (antioxidant, anti-inflammatory, antihypertensive, hypocholesterolemic -all of them linked to metabolic syndrome- and antitumoral) of proteins and peptides from legumes focused on isolation and purification, enzymatic hydrolysis and in vitro gastrointestinal digestion was carried out. The promising potential of bioactive hydrolysates and peptides from pulses has been demonstrated by in vitro tests. However, only a few studies validated these biological activities using animal models. No clinical trials have been carried out yet; so further research is required to elucidate their effective health implications.

Indexed as

FabaceaeMetabolic SyndromeAnimalsAntihypertensive AgentsAntioxidantsPeptidesVegetablesAntihypertensive AgentsAntioxidantsPeptidesantihypertensiveantioxidantbioactive peptideshypocholesterolemiclegumesmetabolic syndrome

Identifiers

PMID36558429
PMCPMC9782127
OpenAlexW4312126345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.