Evidence map›Paper›PMID 36558344›Full record

ReviewNanomaterials (Basel, Switzerland)2022

Nanoparticles in Drug Delivery: From History to Therapeutic Applications.

Obaid Afzal, Abdulmalik S A Altamimi, Muhammad Shahid Nadeem, Sami I Alzarea, Waleed Hassan Almalki, Aqsa Tariq, Bismillah Mubeen, Bibi Nazia Murtaza, Saima Iftikhar, Naeem Riaz and 1 more

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 151 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
151citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

151 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  8. Green synthesis of ZnO/FeRSC advances · 2026
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91 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Obaid AfzalDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al Kharj 11942, Saudi Arabia.ORCID 0000-0002-4188-5592
Abdulmalik S A AltamimiDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al Kharj 11942, Saudi Arabia.
Muhammad Shahid NadeemDepartment of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0003-4112-0925
Sami I AlzareaDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.ORCID 0000-0003-4007-4023
Waleed Hassan AlmalkiDepartment of Pharmacology, College of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Aqsa TariqInstitute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore 54000, Pakistan.
Bismillah MubeenInstitute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore 54000, Pakistan.ORCID 0000-0002-4095-6467
Bibi Nazia MurtazaDepartment of Zoology, Abbottabad University of Science and Technology (AUST), Abbottabad 22310, Pakistan.
Saima IftikharSchool of Biological Sciences, University of Punjab, Lahore 54000, Pakistan.ORCID 0000-0002-0410-6959
Naeem RiazDepartment of Pharmacy, COMSATS University, Abbottabad 22020, Pakistan.
Imran KazmiDepartment of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0003-1881-5219

Funding

Umm al-Qura University 224UQU4310387DSR03
6 · The paper itself

Abstract

Current research into the role of engineered nanoparticles in drug delivery systems (DDSs) for medical purposes has developed numerous fascinating nanocarriers. This paper reviews the various conventionally used and current used carriage system to deliver drugs. Due to numerous drawbacks of conventional DDSs, nanocarriers have gained immense interest. Nanocarriers like polymeric nanoparticles, mesoporous nanoparticles, nanomaterials, carbon nanotubes, dendrimers, liposomes, metallic nanoparticles, nanomedicine, and engineered nanomaterials are used as carriage systems for targeted delivery at specific sites of affected areas in the body. Nanomedicine has rapidly grown to treat certain diseases like brain cancer, lung cancer, breast cancer, cardiovascular diseases, and many others. These nanomedicines can improve drug bioavailability and drug absorption time, reduce release time, eliminate drug aggregation, and enhance drug solubility in the blood. Nanomedicine has introduced a new era for drug carriage by refining the therapeutic directories of the energetic pharmaceutical elements engineered within nanoparticles. In this context, the vital information on engineered nanoparticles was reviewed and conferred towards the role in drug carriage systems to treat many ailments. All these nanocarriers were tested in vitro and in vivo. In the coming years, nanomedicines can improve human health more effectively by adding more advanced techniques into the drug delivery system.

Indexed as

drug deliverynanomedicinenanoparticlespersonalized medicinetherapeutics

Identifiers

PMID36558344
PMCPMC9781272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.