Evidence map›Paper›PMID 36558269›Full record

ReviewNanomaterials (Basel, Switzerland)2022

Ceramic Nanomaterials in Caries Prevention: A Narrative Review.

Mohammed Zahedul Islam Nizami, Veena Wenqing Xu, Iris Xiaoxue Yin, Christie Ying Kei Lung, John Yun Niu, Chun Hung Chu

Open access · goldAbstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

  1. Next-Gen Restorative Materials to Revolutionise Smiles.Bioengineering (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mohammed Zahedul Islam NizamiFaculty of Dentistry, University of Hong Kong, Hong Kong SAR 999077, China.ORCID 0000-0002-6041-1907
Veena Wenqing XuFaculty of Dentistry, University of Hong Kong, Hong Kong SAR 999077, China.ORCID 0000-0001-9084-4001
Iris Xiaoxue YinFaculty of Dentistry, University of Hong Kong, Hong Kong SAR 999077, China.ORCID 0000-0003-1167-2999
Christie Ying Kei LungFaculty of Dentistry, University of Hong Kong, Hong Kong SAR 999077, China.ORCID 0000-0002-5320-2373
John Yun NiuFaculty of Dentistry, University of Hong Kong, Hong Kong SAR 999077, China.ORCID 0000-0002-3471-180X
Chun Hung ChuFaculty of Dentistry, University of Hong Kong, Hong Kong SAR 999077, China.ORCID 0000-0002-8167-0430
University of Hong Kong · HK

Funding

National Natural Science Foundation of China 81870812
6 · The paper itself

Abstract

Ceramic nanomaterials are nanoscale inorganic metalloid solids that can be synthesised by heating at high temperatures followed by rapid cooling. Since the first nanoceramics were developed in the 1980s, ceramic nanomaterials have rapidly become one of the core nanomaterials for research because of their versatility in application and use in technology. Researchers are developing ceramic nanomaterials for dental use because ceramic nanoparticles are more stable and cheaper in production than metallic nanoparticles. Ceramic nanomaterials can be used to prevent dental caries because some of them have mineralising properties to promote the remineralisation of tooth tissue. Ceramic minerals facilitate the remineralisation process and maintain an equilibrium in pH levels to maintain tooth integrity. In addition, ceramic nanomaterials have antibacterial properties to inhibit the growth of cariogenic biofilm. Researchers have developed antimicrobial nanoparticles, conjugated ceramic minerals with antibacterial and mineralising properties, to prevent the formation and progression of caries. Common ceramic nanomaterials developed for caries prevention include calcium-based (including hydroxyapatite-based), bioactive glass-based, and silica-based nanoparticles. Calcium-based ceramic nanomaterials can substitute for the lost hydroxyapatite by depositing calcium ions. Bioactive glass-based nanoparticles contain surface-reactive glass that can form apatite crystals resembling bone and tooth tissue and exhibit chemical bonding to the bone and tooth tissue. Silica-based nanoparticles contain silica for collagen infiltration and enhancing heterogeneous mineralisation of the dentin collagen matrix. In summary, ceramic nanomaterials can be used for caries prevention because of their antibacterial and mineralising properties. This study gives an overview of ceramic nanomaterials for the prevention of dental caries.

Indexed as

cariesdentindentistrynanomaterialsnanoparticlespreventionremineralising

Identifiers

PMID36558269
PMCPMC9786898
OpenAlexW4312127333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.