Evidence map›Paper›PMID 36558192›Full record

ArticleMolecules (Basel, Switzerland)2022

Ratiometric Singlet Oxygen Sensor Based on BODIPY-DPA Dyad.

Alexey A Pakhomov, Anastasia S Belova, Arevik G Khchoyan, Yuriy N Kononevich, Dmitriy S Ionov, Margarita A Maksimova, Anastasiya Yu Frolova, Mikhail V Alfimov, Vladimir I Martynov, Aziz M Muzafarov

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Alexey A PakhomovM.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0001-7757-6452
Anastasia S BelovaA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-7881-5707
Arevik G KhchoyanA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 119991 Moscow, Russia.
Yuriy N KononevichA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0003-3256-7995
Dmitriy S IonovPhotochemistry Center, FSRC "Crystallography and Photonics", Russian Academy of Sciences, 119421 Moscow, Russia.ORCID 0000-0001-7355-589X
Margarita A MaksimovaM.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Anastasiya Yu FrolovaM.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Mikhail V AlfimovPhotochemistry Center, FSRC "Crystallography and Photonics", Russian Academy of Sciences, 119421 Moscow, Russia.
Vladimir I MartynovM.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0003-4923-6842
Aziz M MuzafarovA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-3050-3253

Funding

Russian Science Foundation 19-73-20194
6 · The paper itself

Abstract

Compounds sensitive to reactive oxygen species are widely used in the study of processes in living cells and in the development of therapeutic agents for photodynamic therapy. In the present work, we have synthesized a dyad in which the BODIPY dye is chemically bound to 9,10-diphenylanthracene (DPA). Here, DPA acts as a specific sensor of singlet oxygen and BODIPY as a reference dye. We studied the photophysical properties of the BODIPY-DPA dyad and showed that energy transfer occurs between the chromophores. As a result, the compound has excitation maxima in the absorption region of both DPA and BODIPY, but the fluorescence emission occurs mainly from BODIPY. In the presence of singlet oxygen, the excitation maximum of DPA decreases, while the intensity of the excitation maximum of BODIPY remains almost unchanged. This allows the BODIPY-DPA dyad to be used as a ratiometric sensor of singlet oxygen.

Indexed as

PhotochemotherapySinglet OxygenBoron CompoundsEnergy Transfer4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneBoron CompoundsSinglet OxygenanthraceneBODIPYDPAreactive oxygen speciessensorsinglet oxygen

Identifiers

PMID36558192
PMCPMC9780792

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.