Evidence map›Paper›PMID 36558154›Full record

ReviewMolecules (Basel, Switzerland)2022

Raman Spectroscopy of Carotenoid Compounds for Clinical Applications-A Review.

Joy Udensi, James Loughman, Ekaterina Loskutova, Hugh J Byrne

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
11.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 51 citations in OpenAlex.

  1. Trial
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  7. Article
  8. Article
  9. Article
  10. Raman signatures ofFrontiers in microbiology · 2026
    Article
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  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joy UdensiFOCAS Research Institute, Technological University Dublin, City Campus, Camden Row, Dublin 8, D08 CKP1 Dublin, Ireland.ORCID 0000-0001-8107-4201
James LoughmanSchool of Physics and Clinical and Optometric Sciences, Technological University Dublin, City Campus, Grangegorman, Dublin 7, D07 EWV4 Dublin, Ireland.
Ekaterina LoskutovaSchool of Physics and Clinical and Optometric Sciences, Technological University Dublin, City Campus, Grangegorman, Dublin 7, D07 EWV4 Dublin, Ireland.
Hugh J ByrneFOCAS Research Institute, Technological University Dublin, City Campus, Camden Row, Dublin 8, D08 CKP1 Dublin, Ireland.ORCID 0000-0002-1735-8610
Technological University Dublin · IE

Funding

Technological University Dublin Postgraduate Scholarship 2020
6 · The paper itself

Abstract

Carotenoid compounds are ubiquitous in nature, providing the characteristic colouring of many algae, bacteria, fruits and vegetables. They are a critical component of the human diet and play a key role in human nutrition, health and disease. Therefore, the clinical importance of qualitative and quantitative carotene content analysis is increasingly recognised. In this review, the structural and optical properties of carotenoid compounds are reviewed, differentiating between those of carotenes and xanthophylls. The strong non-resonant and resonant Raman spectroscopic signatures of carotenoids are described, and advances in the use of Raman spectroscopy to identify carotenoids in biological environments are reviewed. Focus is drawn to applications in nutritional analysis, optometry and serology, based on in vitro and ex vivo measurements in skin, retina and blood, and progress towards establishing the technique in a clinical environment, as well as challenges and future perspectives, are explored.

Indexed as

LuteinSpectrum Analysis, Ramanbeta CaroteneCarotenoidsHumansXanthophyllsZeaxanthinsbeta CaroteneCarotenoidsLuteinXanthophyllsZeaxanthinsbeta carotenebloodcarotenoidsluteinlycopeneoptometryRaman spectroscopyskinzeaxanthin

Identifiers

PMID36558154
PMCPMC9784873
OpenAlexW4312210002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.