Evidence map›Paper›PMID 36558129›Full record

ArticleMolecules (Basel, Switzerland)2022

2-(2-(Dimethylamino)vinyl)-4

Dmitrii L Obydennov, Diana I Nigamatova, Alexander S Shirinkin, Oleg E Melnikov, Vladislav V Fedin, Sergey A Usachev, Alena E Simbirtseva, Mikhail Y Kornev, Vyacheslav Y Sosnovskikh

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Synthesis of Heteroaromatic Compounds.Molecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Dmitrii L ObydennovInstitute of Natural Sciences and Mathematics, Ural Federal University, 620000 Ekaterinburg, Russia.ORCID 0000-0002-6659-9832
Diana I NigamatovaInstitute of Natural Sciences and Mathematics, Ural Federal University, 620000 Ekaterinburg, Russia.
Alexander S ShirinkinInstitute of Natural Sciences and Mathematics, Ural Federal University, 620000 Ekaterinburg, Russia.ORCID 0000-0002-4650-8446
Oleg E MelnikovInstitute of Natural Sciences and Mathematics, Ural Federal University, 620000 Ekaterinburg, Russia.
Vladislav V FedinInstitute of Natural Sciences and Mathematics, Ural Federal University, 620000 Ekaterinburg, Russia.ORCID 0000-0002-2925-7104
Sergey A UsachevInstitute of Natural Sciences and Mathematics, Ural Federal University, 620000 Ekaterinburg, Russia.ORCID 0000-0001-8374-3587
Alena E SimbirtsevaInstitute of Natural Sciences and Mathematics, Ural Federal University, 620000 Ekaterinburg, Russia.
Mikhail Y KornevInstitute of Natural Sciences and Mathematics, Ural Federal University, 620000 Ekaterinburg, Russia.
Vyacheslav Y SosnovskikhInstitute of Natural Sciences and Mathematics, Ural Federal University, 620000 Ekaterinburg, Russia.ORCID 0000-0002-8956-0973
Ural Federal University · RU

Funding

Russian Science Foundation 18-13-00186
6 · The paper itself

Abstract

A straightforward approach for the construction of the new class of conjugated pyrans based on enamination of 2-methyl-4-pyrones with DMF-DMA was developed. 2-(2-(Dimethylamino)vinyl)-4-pyrones are highly reactive substrates that undergo 1,6-conjugate addition/elimination or 1,3-dipolar cycloaddition/elimination followed by substitution of the dimethylamino group without ring opening. This strategy includes selective transformations leading to conjugated and isoxazolyl-substituted 4-pyrone structures. The photophysical properties of the prepared 4-pyrones were determined in view of further design of novel merocyanine fluorophores. A solvatochromism was found for enamino-substituted 4-pyrones accompanied by a strong increase in fluorescence intensity in alcohols. The prepared conjugated structures demonstrated valuable photophysical properties, such as a large Stokes shift (up to 204 nm) and a good quantum yield (up to 28%).

Indexed as

PyransPyronesPyransPyrones1,6-conjugate addition4-pyronecycloadditionDMF-DMAenaminationfluorophoremerocyaninesolvatochromism

Identifiers

PMID36558129
PMCPMC9788530
OpenAlexW4312211270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.