Evidence map›Paper›PMID 36557980›Full record

ArticleMolecules (Basel, Switzerland)2022

Antibacterial and Physical Properties of PVM/MA Copolymer- Incorporated Polymethyl Methacrylate as a Novel Antimicrobial Acrylic Resin Material.

Christopher Lai, Ashten Nguyen, Lynna Ye, Jessica Hao, Hyun Koo, Francis Mante, Fusun Ozer

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Poly(methyl vinyl ether-Polymers · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Ingredients in Commercially Available Mouthwashes.International dental journal · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Christopher LaiPenn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Ashten NguyenPenn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Lynna YeCollege of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
Jessica HaoPenn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Hyun KooDepartment of Orthodontics and Divisions of Pediatric Dentistry and Community Oral Health, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Francis ManteDepartment of Restorative Dentistry, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-9656-9784
Fusun OzerDepartment of Restorative Dentistry, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
University of Pennsylvania · USUniversity of the Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymethyl methacrylate (PMMA), an acrylic resin used in orthodontic appliances and removable dentures for its biocompatibility and esthetics, may harbor bacteria on its surface. The present study investigated a new PMMA formula with Gantrez: an antibacterial copolymer of methyl vinyl ether and maleic acid (PVM/MA). Samples were tested for mechanical properties (surface hardness, flexural strength, water sorption, and water solubility) and effects against Streptococcus mutans. Six groups (0%-control, 5%, 10%, 15%, 20%, and 25% Gantrez) of n = 12 were fabricated for physical property tests and analyzed with one-way ANOVA and Prism 6. From these results, three groups (0%, 5%, and 10% Gantrez) were selected for antibacterial tests, and data were analyzed with one-way ANOVA and Tukey’s multiple comparison test. Adding 5% and 10% Gantrez into PMMA significantly decreased S. mutans adhesion. There was no significant difference between the control vs. 5%, 10%, 15%, and 20% Gantrez (p > 0.05) for surface hardness, the control vs. 5% Gantrez (p > 0.05) for flexural strength, and the control vs. 5 and 10% Gantrez for water sorption and water solubility. Overall, incorporating 5% Gantrez into PMMA may be a promising solution to reduce bacterial adhesion without changing the acrylic resin’s physical properties.

Indexed as

Anti-Infective AgentsPolymethyl MethacrylateAcrylic ResinsAnti-Bacterial AgentsMaleatesMaterials TestingPolyvinylsSurface PropertiesWaterAcrylic ResinsAnti-Bacterial AgentsAnti-Infective AgentsMaleatesPolymethyl Methacrylatepolyvinylmethoxyethylene-maleic anhydride copolymerPolyvinylsWateracrylic resinsantibacterial propertiesflexural strengthGantrezorthodontic appliancesphysical propertiespolymethyl methacrylatesurface hardnesswater solubilitywater sorption

Identifiers

PMID36557980
PMCPMC9781081
OpenAlexW4311366978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.