Evidence map›Paper›PMID 36557948›Full record

ArticleMolecules (Basel, Switzerland)2022

Antitrypanosomal, Antitopoisomerase-I, and Cytotoxic Biological Evaluation of Some African Plants Belonging to Crassulaceae; Chemical Profiling of Extract Using UHPLC/QTOF-MS/MS.

Mostafa M Hegazy, Wael M Afifi, Ahmed M Metwaly, Mohamed M Radwan, Muhamad Abd-Elraouf, Ahmed B M Mehany, Eman Ahmed, Shymaa Enany, Shahd Ezzeldin, Adel E Ibrahim and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Mostafa M HegazyDepartment of Pharmacognosy and Medicinal Plants, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt.ORCID 0000-0001-8975-9424
Wael M AfifiDepartment of Pharmacognosy and Medicinal Plants, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt.ORCID 0000-0002-7388-253X
Ahmed M MetwalyDepartment of Pharmacognosy and Medicinal Plants, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt.ORCID 0000-0001-8566-1980
Mohamed M RadwanNational Center for Natural Products Research, University of Mississippi, University, MS 38677, USA.
Muhamad Abd-ElraoufDepartment of Pharmacognosy and Medicinal Plants, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt.
Ahmed B M MehanyZoology Department, Faculty of Science, Al-Azhar University, Cairo 11884, Egypt.ORCID 0000-0002-9913-5380
Eman AhmedDepartment of Pharmacology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt.ORCID 0000-0003-0973-2630
Shymaa EnanyDepartment of Microbiology and Immunology, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Shahd EzzeldinDepartment of Pharmacology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt.
Adel E IbrahimNatural and Medical Sciences Research Center, University of Nizwa, Birkat Al Mauz, P.O. Box 33, Nizwa 616, Oman.ORCID 0000-0001-7421-1220
Sami El DeebNatural and Medical Sciences Research Center, University of Nizwa, Birkat Al Mauz, P.O. Box 33, Nizwa 616, Oman.ORCID 0000-0001-6417-4737
Ahmad E MostafaDepartment of Pharmacognosy and Medicinal Plants, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt.ORCID 0000-0002-0379-9802
Al-Azhar University · EGSuez Canal University · EGUniversity of Nizwa · OMSinai University · EGUniversity of Mississippi · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In our continuous study for some African plants as a source for antitrypanosomally and cytotoxic active drugs, nine different plants belonging to the Crassulaceae family have been selected for the present study.

Indexed as

Antineoplastic AgentsTandem Mass SpectrometryAfrican PeopleChromatography, High Pressure LiquidFlavonoidsHumansPlant ExtractsAntineoplastic AgentsFlavonoidsPlant ExtractsantitrypanosomalCrassulaceaecytotoxicflavonoidsphenolicsUHPLC/QTOF-MS

Identifiers

PMID36557948
PMCPMC9785725
OpenAlexW4311389147

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.