Evidence map›Paper›PMID 36557924›Full record

ArticleMolecules (Basel, Switzerland)2022

Polyphenolic Profile of Tunisian Thyme (

Kheiria Hcini, Abir Bahi, Monia Bendhifi Zarroug, Mouna Ben Farhat, Antonio Abel Lozano-Pérez, José Luis Cenis, María Quílez, Sondes Stambouli-Essassi, Maria José Jordán

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Exploring the Traditional Uses ofPharmaceuticals (Basel, Switzerland) · 2023
    Article
  5. Review
  6. Effect ofNutrients · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kheiria HciniBiodiversity, Biotechnology and Climate Change Laboratory (LR11ES09), Department of Life Sciences, Faculty of Science of Tunis, University of Tunis El Manar, Tunis 2092, Tunisia.
Abir BahiLaboratory of Analysis, Treatment and Valorisation of Pollutants of the Environment and Products, Faculty of Pharmacy, University of Monastir, Monastir 5000, Tunisia.ORCID 0000-0003-1494-9834
Monia Bendhifi ZarrougDepartment of Biological Engineering, Research Unit of Active Biomolecules Valorisation, Higher Institute of Applied Biology of Medenine , University of Gabes, Gabes 6029, Tunisia.
Mouna Ben FarhatLaboratoire des PlantesExtrêmophiles, Centre de Biotechnologie de Borj-Cédria, BP 901, Hammam-Lif 2050, Tunisia.
Antonio Abel Lozano-PérezDepartamento de Biotecnología, Genómica y Mejora Vegetal, Instituto Murciano de Investigación y DesarrolloAgrario y Medioambiental (IMIDA), La Alberca, 30150 Murcia, Spain.ORCID 0000-0002-5749-3737
José Luis CenisDepartamento de Biotecnología, Genómica y Mejora Vegetal, Instituto Murciano de Investigación y DesarrolloAgrario y Medioambiental (IMIDA), La Alberca, 30150 Murcia, Spain.
María QuílezDepartamento de Desarrollo Rural, Enología y Agricultura Sostenible, Instituto Murciano de Investigación y Desarrollo Agrario y Medioambiental (IMIDA), La Alberca, 30150 Murcia, Spain.
Sondes Stambouli-EssassiBiodiversity, Biotechnology and Climate Change Laboratory (LR11ES09), Department of Life Sciences, Faculty of Science of Tunis, University of Tunis El Manar, Tunis 2092, Tunisia.
Maria José JordánDepartamento de Desarrollo Rural, Enología y Agricultura Sostenible, Instituto Murciano de Investigación y Desarrollo Agrario y Medioambiental (IMIDA), La Alberca, 30150 Murcia, Spain.ORCID 0000-0002-3523-4670

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the last decade there has been growing interest in the formulation of new cosmetic, food and pharmaceutical products containing natural compounds with antioxidant activity and other beneficial properties. Aromatic and medicinal plants have always been the major source of bioactive compounds, especially, wild thyme (Thymbra capitata L.), which has been used since ancient times for its valuable health benefits that could be attributed to the richness of polyphenolic compounds. This study was undertaken with the following aims: to estimate the total polyphenolic content (TPC); to evaluate the antioxidant activity; to identify and quantify the phenolic compounds of post-distilled residues of Tunisian thyme, and their contribution to the antioxidant activity. The TPC, as determined by the Folin−Ciocalteu method, was found to reach the values of 126.7 and 107.84 mg gallic acid equivalent/g plant dry weight (mg GAE/g PDW). The antioxidant activity, which is assessed by DPPH and FRAP assays, reached the values of 42.97−45.64 μg/mL and 42.22−50.21 mMFe2+/mg PDW, respectively. HPLC analysis revealed the presence of fourteen polyphenolic compounds, of which diosmin and rosmarinic acid were found to be the most abundant (24.26 to 33.80 and 22.0.1 to 26.29 mg/g PDW, respectively). An important correlation was found between the antioxidant activity and several identified phenolic compounds (p < 0.05). The findings revealed that thyme post-distilled residues have an effective natural antioxidant potential due to their high concentration of bioactive molecules, and they appear to be useful in the pharmaceutical, cosmetic, and food industries, with beneficial effects on human health. Therefore, supplementing a balanced diet with herbs may have beneficial health effects.

Indexed as

LamiaceaePlants, MedicinalThymus PlantAntioxidantsGallic AcidHumansPhenolsPlant ExtractsAntioxidantsGallic AcidPhenolsPlant Extractsantioxidant activitycorrelationDPPHFRAPHPLCpolyphenolic compoundspost-distilled residuesThymbra capitata L.total polyphenolic content

Identifiers

PMID36557924
PMCPMC9780846

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.