ArticleMolecules (Basel, Switzerland)2022
A Dual-Mode Method Based on Aptamer Recognition and Time-Resolved Fluorescence Resonance Energy Transfer for Histamine Detection in Fish.
Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 14 citations in OpenAlex.
- Advancing Analytical Technologies for Rapid Food Freshness Detection: A Comprehensive Review.Foods (Basel, Switzerland) · 2026Review
- Current Analytical Methods and Recent Advances in Histamine Analysis in Fish and Fish Products: A Systematic Review.Foods (Basel, Switzerland) · 2026Review
- Dual-signal histamine aptasensor design based on SERS and electrochemical effects of gold nanomaterials.Mikrochimica acta · 2026Article
- Advances in Aptamer-Based Biosensors for the Detection of Foodborne Mycotoxins.Molecules (Basel, Switzerland) · 2024Review
- A Colorimetric/Fluorescent Dual-Mode Aptasensor forFoods (Basel, Switzerland) · 2023Article
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
Histamine produced via the secretion of histidine decarboxylase by the bacteria in fish muscles is a toxic biogenic amine and of significant concern in food hygiene, since a high intake can cause poisoning in humans. This study proposed a fluorometric and colorimetric dual-mode specific method for the detection of histamine in fish, based on the fluorescence labeling of a histamine specific aptamer via the quenching and optical properties of gold nanoparticles (AuNPs). Due to the fluorescence resonance energy transfer phenomenon caused by the proximity of AuNPs and NaYF4:Ce/Tb, resulting in the quenching of the fluorescence signal in the detection system, the presence of histamine will compete with AuNPs to capture the aptamer and release it from the AuNP surface, inducing fluorescence recovery. Meanwhile, the combined detection of the two modes showed good linearity with histamine concentration, the linear detection range of the dual-mode synthesis was 0.2-1.0 μmol/L, with a detection limit of 4.57 nmol/L. Thus, this method has good selectivity and was successfully applied to the detection of histamine in fish foodstuffs with the recoveries of 83.39~102.027% and 82.19~105.94% for
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