Evidence map›Paper›PMID 36557710›Full record

ReviewMicroorganisms2022

The Role of Gut Bacteriome in Asthma, Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnoea.

Andras Bikov, Silvano Dragonieri, Balazs Csoma, Carmen Mazzuca, Panaiotis Finamore, Giulia Rocchi, Lorenza Putignani, Michele Guarino, Simone Scarlata

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Andras BikovWythenshawe Hospital, Manchester University NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK.ORCID 0000-0002-8983-740X
Silvano DragonieriDepartment of Respiratory Diseases, University of Bari Aldo Moro, 11 Piazza G. Cesare, 70124 Bari, Italy.
Balazs CsomaWythenshawe Hospital, Manchester University NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK.ORCID 0000-0002-9425-1219
Carmen MazzucaUnit of Internal Medicine, Campus Bio-Medico University Hospital, 00128 Rome, Italy.
Panaiotis FinamoreUnit of Internal Medicine, Campus Bio-Medico University Hospital, 00128 Rome, Italy.ORCID 0000-0002-8608-9223
Giulia RocchiDepartment of Science and Engineering for Human and the Environment, Campus Bio-Medico University of Rome, 00128 Rome, Italy.ORCID 0000-0002-4378-1009
Lorenza PutignaniDepartment of Diagnostics and Laboratory Medicine, Bambino Gesù Children's Hospital, 00165 Rome, Italy.ORCID 0000-0003-0134-2830
Michele GuarinoUnit of Gastroenterology, Campus Bio-Medico University Hospital, 00128 Rome, Italy.
Simone ScarlataUnit of Internal Medicine, Campus Bio-Medico University Hospital, 00128 Rome, Italy.
Università Campus Bio-Medico · ITBambino Gesù Children's Hospital · ITManchester University NHS Foundation Trust · GBSemmelweis University · HUUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human body contains a very complex and dynamic ecosystem of bacteria. The bacteriome interacts with the host bi-directionally, and changes in either factor impact the entire system. It has long been known that chronic airway diseases are associated with disturbances in the lung bacteriome. However, less is known about the role of gut bacteriome in the most common respiratory diseases. Here, we aim to summarise the evidence concerning the role of the intestinal bacteriome in the pathogenesis and disease course of bronchial asthma, chronic obstructive pulmonary disease, and obstructive sleep apnea. Furthermore, we discuss the consequences of an altered gut bacteriome on the most common comorbidities of these lung diseases. Lastly, we also reflect on the therapeutic potential of influencing the gut microbiome to improve disease outcomes.

Indexed as

bronchial asthmachronic obstructive pulmonary diseasegut microbiomehypoxemiainflammationmicrobiomeobstructive sleep apnea

Identifiers

PMID36557710
PMCPMC9781820
OpenAlexW4311387381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.