Evidence map›Paper›PMID 36557625›Full record

ArticleMicroorganisms2022

Ubiquitin-Conjugating Enzymes Ubc1 and Ubc4 Mediate the Turnover of Hap4, a Master Regulator of Mitochondrial Biogenesis in

Denise Capps, Arielle Hunter, Mengying Chiang, Tammy Pracheil, Zhengchang Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Genes · 2024
    Article
  2. Lifespan regulation by targeting heme signaling in yeast.bioRxiv : the preprint server for biology · 2024
    Article
  3. Inactivation ofInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Denise CappsDepartment of Biological Sciences, University of New Orleans, New Orleans, LA 70148, USA.
Arielle HunterDepartment of Biological Sciences, University of New Orleans, New Orleans, LA 70148, USA.
Mengying ChiangDepartment of Biological Sciences, University of New Orleans, New Orleans, LA 70148, USA.
Tammy PracheilDepartment of Biological Sciences, University of New Orleans, New Orleans, LA 70148, USA.
Zhengchang LiuDepartment of Biological Sciences, University of New Orleans, New Orleans, LA 70148, USA.
University of New Orleans · US

Funding

Amino Acid Sensing and Signaling in YeastR15GM094772 · NIGMS · UNIVERSITY OF NEW ORLEANS · PI LIU, ZHENGCHANG · 2011 to 2011
$284k
NIGMS NIH HHS R15 GM094772NIH HHS 1R15GM094772-01A1
6 · The paper itself

Abstract

Mitochondrial biogenesis is tightly regulated in response to extracellular and intracellular signals, thereby adapting yeast cells to changes in their environment. The Hap2/3/4/5 complex is a master transcriptional regulator of mitochondrial biogenesis in yeast. Hap4 is the regulatory subunit of the complex and exhibits increased expression when the Hap2/3/4/5 complex is activated. In cells grown under glucose derepression conditions, both the

Indexed as

Hap4mitochondrial dysfunctionproteasomeprotein turnoverSaccharomyces cerevisiaetranscription factorUbc1Ubc4ubiquitin-conjugating enzyme (E2 enzyme)

Identifiers

PMID36557625
PMCPMC9787919
OpenAlexW4310478823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.