Evidence map›Paper›PMID 36557578›Full record

ReviewMicroorganisms2022

Antimicrobial Activity of Honey against Oral Microorganisms: Current Reality, Methodological Challenges and Solutions.

Diego Romário-Silva, Severino Matias Alencar, Bruno Bueno-Silva, Janaína de Cássia Orlandi Sardi, Marcelo Franchin, Rafaela Durrer Parolina de Carvalho, Thayná Ellen de Sousa Alves Ferreira, Pedro Luiz Rosalen

Abstract readReview
In one paragraph

Review in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Honey Compounds Exhibit Antibacterial Effects AgainstAntibiotics (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Honey as a Natural Antimicrobial.Antibiotics (Basel, Switzerland) · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Antimicrobial and antibiofilm activities of Brazilian organic honey against oral microorganisms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  16. Review
  17. Article
  18. The Antibacterial Properties of Polish Honey againstAntibiotics (Basel, Switzerland) · 2023
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Diego Romário-SilvaDepartment of Biosciences, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba 13414-903, Brazil.
Severino Matias AlencarDepartment of Agri-Food Industry, Food and Nutrition, Luiz de Queiroz College of Agriculture (Escola Superior de Agricultura "Luiz de Queiroz"-ESALQ), University of São Paulo, Piracicaba 13418-900, Brazil.ORCID 0000-0002-6637-7973
Bruno Bueno-SilvaDental Research Division, Guarulhos University, Guarulhos 07023-070, Brazil.ORCID 0000-0003-3275-5910
Janaína de Cássia Orlandi SardiResearch Program in Integrated Dental Sciences, University of Cuiabá, Cuiabá 78065-900, Brazil.
Marcelo FranchinSchool of Dentistry, Federal University of Alfenas (Unifal-MG), Alfenas 37130-001, Brazil.
Rafaela Durrer Parolina de CarvalhoDepartment of Biosciences, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba 13414-903, Brazil.ORCID 0000-0002-3251-3367
Thayná Ellen de Sousa Alves FerreiraDepartment of Biosciences, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba 13414-903, Brazil.ORCID 0000-0003-1608-0060
Pedro Luiz RosalenDepartment of Biosciences, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba 13414-903, Brazil.ORCID 0000-0003-0812-4027

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 141129/2017-4 and 306673/2019-3Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) Finance Code 001
6 · The paper itself

Abstract

Honey has been shown to have antimicrobial activity against different microorganisms, but its effects on oral biofilms are largely unknown. In this review, we analyzed the currently available literature on the antimicrobial activity of honey against oral biofilms in order to determine its potential as a functional food in the treatment and/or prevention of oral diseases. Here, we compare studies reporting on the antimicrobial activity of honey against systemic and oral bacteria, discuss methodological strategies, and point out current gaps in the literature. To date, there are no consistent studies supporting the use of honey as a therapy for oral diseases of bacterial origin, but current evidence in the field is promising. The lack of studies examining the antibiofilm activity of honey against oral microorganisms reveals a need for additional research to better define aspects such as chemical composition, the mechanism(s) of action, and antimicrobial action.

Indexed as

antibiofilm activityantimicrobial activitycomplementary therapyfunctional foodhoneyoral health

Identifiers

PMID36557578
PMCPMC9781356

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.