ArticleMetabolites2022
Long-Term Impacts of Diurnal Temperature Range on Mortality and Cardiovascular Disease: A Nationwide Prospective Cohort Study.
Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Mapping the Burden of Ischemic Stroke Attributable to Temperature Variation under Climate Change Scenarios Accounting for Long-Term Adaptation.Environmental health perspectives · 2026Article
- Diurnal temperature range and daily mean temperature in relation to multimorbidity among middle-aged or older Chinese adults: insights from the CHARLS.BMC public health · 2026Article
- Interactive effects of diurnal temperature range and air pollution on myocardial infarction incidence: an individual-level case-crossover study.Scientific reports · 2026Article
- CVD Environmental Health Disparities Tool: systematic evidence mapping of psychosocial stressors, environmental exposures, and cardiovascular diseases to inform disparities research and action.Environmental health : a global access science source · 2026Review
- Diurnal temperature range and hospital admission due to cardiovascular diseases: A systematic review and meta-analysis study.International journal of cardiology. Cardiovascular risk and prevention · 2025Review
- Burden of mortality attributable to diurnal temperature range in Thailand: a nationwide case-crossover analysis from 2007 to 2021.Tropical medicine and health · 2025Article
- The association between temperature variability, morbidity and mortality for specific categories of disease: A systematic review and meta-analysis.Hygiene and environmental health advances · 2025Article
- Association of diurnal temperature range and childhood asthma: a population-based cross-sectional study in a Tropical City, China.BMC public health · 2025Article
- Interactive effects of atmospheric oxidative pollutants and heat on circulatory disease mortality.Frontiers in public health · 2025Article
- Diurnal temperature range and hypertension: cross-sectional and longitudinal findings from the China Health and Retirement Longitudinal Study (CHARLS).BMC public health · 2024Article
- External exposome and all-cause mortality in European cohorts: the EXPANSE project.Frontiers in epidemiology · 2024Article
- Research on the relationship between common metabolic syndrome and meteorological factors in Wuhu, a subtropical humid city of China.BMC public health · 2023Article
- Air pollution is associated with abnormal left ventricular diastolic function: a nationwide population-based study.BMC public health · 2023Article
- Augmented temperature fluctuation aggravates muscular atrophy through the gut microbiota.Nature communications · 2023Article
- Temperature variability increases the onset risk of ischemic stroke: A 10-year study in Tianjin, China.Frontiers in neurology · 2023Article
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15 authors.
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Abstract
Previous studies have documented the associations between short-term diurnal temperature range (DTR) exposure and cardiovascular disease (CVD) via time-series analyses. However, the long-term impacts of DTR through a population-based prospective cohort have not been elucidated thoroughly. This study aimed to quantify the longitudinal association of DTR exposure with all-cause mortality and CVD in a nationwide prospective cohort and, by extension, project future DTR changes across China under climate change. We included 22,702 adults (median age 56.1 years, 53.7% women) free of CVD at baseline from a nationwide cross-sectional study in China during 2012-2015, and examined three health outcomes during a follow-up survey in 2018-2019. We estimated the chronic DTR exposure as baseline annual mean daily maximum minus minimum temperature. The Cox proportional hazards regression was adopted to assess the multivariable-adjusted hazard ratio and its corresponding 95% confidence interval (95% CI). We employed 31 downscaled global climate models under two shared socioeconomic pathways for future projection. During the median follow-up period of ~5 years, 1096 subjects died due to all causes while 993 and 597 individuals developed fatal or nonfatal CVD and fatal or nonfatal stroke, respectively. The cumulative incidence rates of all-cause mortality, CVD, and stroke were 10.49, 9.45, and 5.64 per 1000 person-years, respectively. In the fully adjusted models, the risks for all-cause mortality, CVD, and stroke would increase by 13% (95% CI: 8-18%), 12% (95% CI: 7-18%), and 9% (95% CI: 2-16%) per 1 °C increment in DTR, respectively. Moreover, linear positive associations for the concentration-response curves between DTR and mortality and CVD were observed. We also found significantly greater DTR-related mortality risks among rural residents than their urban counterparts. The DTR changes featured a dipole pattern across China under a warming climate. The southern (northern) China would experience increased (decreased) DTR exposure by the end of 21st century. The present study indicates that chronic DTR exposure can exert long-term impacts on mortality and CVD risks, which may inform future public health policies on DTR-related susceptible population and regions.
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