Evidence map›Paper›PMID 36557312›Full record

ReviewMetabolites2022

Gingerol, a Natural Antioxidant, Attenuates Hyperglycemia and Downstream Complications.

Khalid Saad Alharbi, Muhammad Shahid Nadeem, Obaid Afzal, Sami I Alzarea, Abdulmalik S A Altamimi, Waleed Hassan Almalki, Bismillah Mubeen, Saima Iftikhar, Luqman Shah, Imran Kazmi

Open access · goldAbstract readReview
In one paragraph

Review in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
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  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Biomedical reports · 2024
    Article
  13. Research progress of ginger in the treatment of gastrointestinal tumors.World journal of gastrointestinal oncology · 2023
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Khalid Saad AlharbiDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.
Muhammad Shahid NadeemDepartment of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0003-4112-0925
Obaid AfzalDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.ORCID 0000-0002-4188-5592
Sami I AlzareaDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.ORCID 0000-0003-4007-4023
Abdulmalik S A AltamimiDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.
Waleed Hassan AlmalkiDepartment of Pharmacology, College of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.ORCID 0000-0001-5890-6030
Bismillah MubeenInstitute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore 54000, Pakistan.ORCID 0000-0002-4095-6467
Saima IftikharSchool of Biological Sciences, University of Punjab, Lahore 54000, Pakistan.ORCID 0000-0002-0410-6959
Luqman ShahDepartment of Biochemistry, Faculty of Science, Hazara University, Mansehra 21300, Pakistan.
Imran KazmiDepartment of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Jouf University · SAKing Abdulaziz University · SAPrince Sattam Bin Abdulaziz University · SAHazara University · PKUmm al-Qura University · SAUniversity of Lahore · PKUniversity of the Punjab · PK

Funding

Umm al-Qura University 224UQU4310387DSR03
6 · The paper itself

Abstract

Hyperglycemia is seen in approximately 68 percent of patients admitted to a medical intensive care unit (ICU). In many acute circumstances, such as myocardial infarction, brain, injury and stroke, it is an independent predictor of mortality. Hyperglycemia is induced by a mix of genetic, environmental, and immunologic variables in people with type 1 diabetes. These factors cause pancreatic beta cell death and insulin insufficiency. Insulin resistance and irregular insulin production cause hyperglycemia in type 2 diabetes patients. Hyperglycemia activates a number of complicated interconnected metabolic processes. Hyperglycemia is a major contributor to the onset and progression of diabetes' secondary complications such as neuropathy, nephropathy, retinopathy, cataracts, periodontitis, and bone and joint issues. Studies on the health benefits of ginger and its constituent's impact on hyperglycemia and related disorders have been conducted and gingerol proved to be a potential pharmaceutically active constituent of ginger (

Indexed as

6-gingerolcataractgingerolHyperglycemianephropathyneuropathyperiodontitisretinopathyZingiber officinale

Identifiers

PMID36557312
PMCPMC9782005
OpenAlexW4312195217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.