Evidence map›Paper›PMID 36557243›Full record

ArticleMetabolites2022

Mannose Receptor Deficiency Impacts Bone Marrow and Circulating Immune Cells during High Fat Diet Induced Obesity.

Jasmine Nour, Annalisa Moregola, Monika Svecla, Lorenzo Da Dalt, Rossella Bellini, Olivier Neyrolles, Gian Paolo Fadini, Yoann Rombouts, Mattia Albiero, Fabrizia Bonacina and 1 more

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Mannose Ligands for Mannose Receptor Targeting.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Jasmine NourDepartment of Excellence of Pharmacological and Biomolecular Sciences, University of Milan, 20133 Milan, Italy.
Annalisa MoregolaDepartment of Excellence of Pharmacological and Biomolecular Sciences, University of Milan, 20133 Milan, Italy.
Monika SveclaDepartment of Excellence of Pharmacological and Biomolecular Sciences, University of Milan, 20133 Milan, Italy.ORCID 0000-0002-7269-7308
Lorenzo Da DaltDepartment of Excellence of Pharmacological and Biomolecular Sciences, University of Milan, 20133 Milan, Italy.ORCID 0000-0002-6298-8689
Rossella BelliniDepartment of Excellence of Pharmacological and Biomolecular Sciences, University of Milan, 20133 Milan, Italy.ORCID 0000-0002-2595-7226
Olivier NeyrollesInstitut de Pharmacologie et de Biologie Structurale, IPBS, University of Toulouse, CNRS, UPS, 31400 Toulouse, France.
Gian Paolo FadiniDepartment of Medicine, University of Padua, 35128 Padua, Italy.
Yoann RomboutsInstitut de Pharmacologie et de Biologie Structurale, IPBS, University of Toulouse, CNRS, UPS, 31400 Toulouse, France.ORCID 0000-0003-4482-2199
Mattia AlbieroDepartment of Medicine, University of Padua, 35128 Padua, Italy.
Fabrizia BonacinaDepartment of Excellence of Pharmacological and Biomolecular Sciences, University of Milan, 20133 Milan, Italy.ORCID 0000-0002-2611-1177
Giuseppe Danilo NorataDepartment of Excellence of Pharmacological and Biomolecular Sciences, University of Milan, 20133 Milan, Italy.ORCID 0000-0002-6081-1257
University of Milan · ITCentre National de la Recherche Scientifique · FRUniversity of Padua · IT

Funding

Fondazione Cariplo 2019-1560Ministero della Salute RF-2019-12370896Progettidi Rilevante Interesse Nazionale K55HLCTelethon Foundation GGP19146
6 · The paper itself

Abstract

The mannose receptor C-type 1 (Mrc1) is a C-type lectin receptor expressed on the immune cells and sinusoidal endothelial cells (ECs) of several tissues, including the bone marrow (BM). Parallel to systemic metabolic alterations and hematopoietic cell proliferation, high-fat diet (HFD) feeding increases the expression of Mrc1 in sinusoidal ECs, thus calling for the investigation of its role in bone marrow cell reprogramming and the metabolic profile during obesity.

Indexed as

bone marrowinflammationMrc1obesity

Identifiers

PMID36557243
PMCPMC9784906
OpenAlexW4311103020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.